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. 2022 Jun 23;239(9):2931–2943. doi: 10.1007/s00213-022-06178-6

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Average self-reported urge to smoke according to the 100-mm VAS scoring system self-assessed by subjects over 240 min following use of a single nicotine pouch (#2 or #3) or cigarette study products (pre-dose is plotted as 0 min). 100 = extreme urge to smoke, 0 = no urge to smoke. A lower score indicates a greater reduction in desire to smoke. For no. #2, n = 22; no. #3, n = 23; cigarette, n = 22. Data plotted with error bars (standard deviation) can be found in the supplementary information (Fig. S2)