Table 3.

Most frequent adverse events

AEs*	Experimental	Control	Total	Articles
Increased respiratory rate	30	34	64	[16]
Increased blood pressure	20	20	40	[16, 20, 26]
Fever	17	22	39	[15, 16, 20, 26]
Elevated ALT	19	15	34	[18, 20]
Anemia	15	17	32	[15, 16, 26]
Sepsis	6	15	21	[15, 16]
Deaths with no cause reported	6	14	20	[15, 16]
Decreased absolute lymphocyte	8	9	17	[16]
Elevated LDH	10	7	17	[18, 26]
Disease progression	5	9	14	[16]
Hypokalemia	9	3	12	[15, 18, 26]
Bacterial infections	9	3	12	[15, 18, 25]
Metabolic alkalosis	5	6	11	[16, 18]
Acute Respiratory Distress Syndrome	4	7	11	[16, 26]
Multiple organ failure	3	8	11	[16, 26]

^*AEs occurring a total of more than 10 times in all studies