. Author manuscript; available in PMC: 2022 Jun 23.

Published in final edited form as: Newborn (Clarksville). 2022 Mar 31;1(1):44–57. doi: 10.5005/jp-journals-11002-0025

Table 1:

Specific human and murine endothelial cell markers

Type of marker	Name of marker	Species expressed	Cells expressed
Constitutive markers expressed in different endothelium	CD31/PECAM-1¹⁵⁴	Human, murine	Endothelial cells, B and T lymphocytes, platelets, monocytes, neutrophils
	Bandeirea simplicifolia lectin binding¹⁵⁵	Murine	Endothelial cells
	Vascular endothelial cadherin^39,156	Human, murine	Endothelial cells, trophoblasts, macrophages
	CD34²⁰	Human, murine	Endothelial cells, hemopoietic precursors
	Thrombomodulin¹⁵⁷	Human, murine	Endothelial cells, smooth muscle cells
Monoclonal antibodies used to identify specific endothelial cells	BMA-120¹⁵⁸	Human	ECs, mesothelium, glomerular epithelium
	EN4¹⁵⁸	Human	Endothelial cells, leukocytes, platelets
	EN 7/44¹⁵⁹	Human	Endothelial cells in tumors and inflammatory tissues
Endothelial cell markers induced by inflammatory cytokines	CD54/ICAM-1^22,160	Human, murine	ECs, leukocytes, epithelium, fibroblasts
Endothelial cell markers induced by inflammatory cytokines	CD62E/E-selectin²¹	Human, murine	Endothelial cells, postcapillary venules
Endothelial cell markers induced by angiogenesis	KDR/Flk-1 (VEGFR-2)^120,132,161	Human, murine	Endothelial cells
	Flt-1 (VEGFR-1)^120,126,162	Human, murine	Endothelial cells
	Tie-1^57,163	Human, murine	Endothelial cells
	Tie-2/Tek^57,163	Human, murine	Endothelial cells

CD, cluster differentiation; PECAM-1, platelet endothelial intercellular adhesion molecule; BMA, biotinylated monoclonal antibody; EN, endothelium antibody; E-selectin, endothelial cells selectin; KDR/Flk-1, kinase insert domain receptor/fetal liver kinase 1; Flt-1, Fms-related receptor tyrosine kinase 1; VEGFR, vascular endothelial growth factor receptor; Tie and Tek, receptor tyrosine kinase genes