Table 4.

Association of expression level of FMNL2 with brain infarcts in all brain samples in the dorsolateral prefrontal cortex from ROSMAP

Infarcts	b	SE	p	pFDR
Gross chronic infarctions in cortex	1.024	0.295	5.21 × 10–4	0.003
Gross subacute infarctions in cortex	0.697	0.467	0.135	0.181
Micro subacute infarctions in cortex	0.017	0.542	0.975	0.975
Chronic infarctions in cortex, regardless of size	0.525	0.226	0.020	0.060
Subacute infarctions in cortex, regardless of size	0.519	0.361	0.151	0.181
Infarctions in cortex, regardless of size/age	0.388	0.206	0.060	0.120

b estimate, SE standard error, p p value, p_FDR FDR adjusted p value. The expression of FMNL2 was increased in pathological AD with gross chronic infarcts compared to pathological AD without gross chronic infarcts (b = 0.792, p = 0.025)