Table 1.
Main clinical and demographic characteristics of patients included in the study
Total sample (n = 186) | Blepharospasm (n = 65) | Cervical dystonia (n = 46) | Hemifacial spasm (n = 40) | Oromandibular dystonia (n = 5) | Focal dystonia (n = 16) | Sialorrhea (n = 14) | |
---|---|---|---|---|---|---|---|
Sex | |||||||
Female | 115 (61.8%) | 46 (70.8%) | 27 (58.7%) | 28 (70%) | 3 (60%) | 8 (50%) | 3 (21.4%) |
Male | 71 (38.2%) | 19 (29.2%) | 19 (41.3%) | 12 (30%) | 2 (40%) | 8 (50%) | 11 (78.6%) |
Age | |||||||
68.2 ± 15 (20–96) | 73.7 ± 12.2 (26–96) | 61 ± 15.1 (20–88) | 72.6 ± 13.3 (43–91) | 55.9 ± 8 (49–68) | 54.7 ± 17.6 (24–83) | 74.9 ± 8.1 (56–85) | |
Years of treatment with BoNT | |||||||
8.7 ± 7.2 (1–33) | 9.1 ± 6.3 (1–31) | 10 ± 7.4 (1–27) | 11.4 ± 8.9 (1–33) | 5.4 ± 2 (2–7) | 4.1 ± 3.2 (1–14) | 2.7 ± 1.4 (1–5) | |
Type of BoNT | |||||||
OnaBoNTA | 98 (52.7%) | 52 (80%) | 1 (2.2%) | 32 (80%) | 1 (20%) | 0 | 12 (85.7%) |
IncoBoNTA | 31 (16.7%) | 13 (20%) | 6 (13%) | 7 (17.5%) | 2 (40%) | 1 (6.2%) | 2 (14.3%) |
AboBoNTA | 57 (30.6%) | 0 | 39 (84.8%) | 1 (2.5%) | 2 (40%) | 15 (93.8%) | 0 |
Dose of BoNT (U) | |||||||
63 ± 55.4 (2.5–500) | 45 ± 19.7 (10–95) | 109 ± 46.9 (33.3–266.7) | 31.1 ± 18.8 (7.5–65) | 59 ± 55.3 (6.7–133.3) | 78.2 ± 62 (16.7–266.7) | 50.7 ± 19 (20–90) |
Data are reported as mean ± standard deviation (range) or number of patients (percentage)
BoNT botulinum toxin