Table 2.

Multiple regression analysis of time to onset of BoNT effect

Model summary	R	R2	Adjusted R2	Standard error	Durbin–Watson
	0.348	0.121	0.065	4,88,630	2037

ANOVA	Sum of squares	Degrees of freedom	Mean squares	F	p value
Regression	563,539	11	51,231	2146	0.020*
Residual	4082,789	171	23,876
Total	4646,328	182

Covariance analysis	B	Standard error	Beta	t	p value
Doses	0.018	0.011	0.163	1.670	0.097
Years of treatment	− 0.063	0.058	− 0.090	− 1.085	0.279
Age	− 0.084	0.029	− 0.249	− 2.879	0.004*
Sex	0.401	0.796	0.039	0.504	0.615
IncobotulinumtoxinA	− 0.224	1.117	− 0.017	− 0.200	0.842
AbobotulinumtoxinA	− 2.225	1.866	− 0.204	− 1.192	0.235
Cervical dystonia	1.389	1.919	0.120	0.723	0.470
Hemifacial spasm	1.401	1.025	0.113	1.367	0.173
Oromandibular dystonia	3.699	2.483	0.120	1.490	0.138
Focal dystonia	1.721	2.265	0.096	0.760	0.448
Sialorrhea	0.273	1.590	0.014	0.172	0.864

As a categorical, non-dichotomous variable, type of toxin was inserted in the statistical model as a dummy variable with onabotulinumtoxin-A as the reference level (thus not present in the table)

Likely, type of disease was inserted as a dummy variable with blepharospasm as the reference level (thus not present in the table)

BoNT botulinum toxin