Table 2.
List of antibodies used in this study
| Antibody | Full name | RRID | Company | Product number | Target | Dilution | AD human | CTE human | Muskox | Bighorn |
|---|---|---|---|---|---|---|---|---|---|---|
| AT8 | AB_223647 | ThermoFisher | MN1020 | Phospho tau, Serine 202, Threonine 205 | 1:500 | ✓ | ✓ | ✓ | ✓ | |
| Collagen IV | AB_445160 | Abcam | AB6586 | Basement membrane of blood vessels | 1:300 | ✓ | ✓ | ✗ | ✗ | |
| CP13 | AB_2314223 | Davies lab | Phospho tau, Serine 202 | 1:1000 | ✓ | ✓ | ✓ | Weak | ||
| dMBP | Denatured myelin basic protein | AB_2140351 | Sigma | AB5864 | Denatured myelin | 1:500 | Weak | Weak | Weak | Weak |
| GFAP | Glial fibrillary acidic protein | AB_880202 | Abcam | 68428 | Astrocytes | 1:1000 | ✓ | ✓ | ✓ | ✓ |
| Iba-1 | Ionized calcium-binding adaptor molecule-1 | AB_839504 | Wako | 019–19741 | Microglia | 1:500 | ✓ | ✓ | ✓ | ✓ |
| MOAB-2 | Amyloid beta antibody | AB_2895168 | MilliporeSigma | MABN254 | Amyloid beta | 1:500 | ✓ | ✓ | ✗ | ✗ |
| PHF-1 | AB_2315150 | Davies lab | Phospho tau, Serine 396, Serine 404 | 1:500 | ✓ | ✓ | ✓ | Weak | ||
| SMI-312 | Anti-phosphorylated neurofilament | AB_2566782 | BioLegend | 837904 | Phosphorylated neurofilaments M and H in axons | 1:1000 | ✓ | ✓ | ✓ | ✓ |
| TDP43 | Anti-TAR DNA-binding protein 43 | AB_2750118 | BioLegend | 829901 | Phosphorylated TDP43 protein, Serine 409, Serine 410 | 1:200 | Weak | Weak | ✗ | ✗ |