Table 2.

The BGM analysis of BDNF found 23 pairs of coevolving sites out of 261 total sites to be statistically significant (with a posterior probability threshold of 0.5).

#	Site 1	Site 2	P [Site 1 –> Site 2]	P [Site 2 –> Site 1]	P [Site 1 < –> Site 2]	Site 1 subs	Site 2 subs	Shared subs
1	5	67	0.52	0.32	0.84	1	1	1
2	25	49	0.022	0.67	0.69	8	6	3
3	27	109	0.12	0.45	0.57	2	1	1
4	30	119	0.2	0.56	0.75	6	12	4
5	33	119	0.12	0.72	0.84	3	12	3
6	39	103	0.22	0.58	0.8	8	4	3
7	49	85	0.48	0.049	0.53	6	3	2
8	49	86	0.36	0.55	0.91	6	5	3
9	50	69	0.31	0.27	0.58	1	2	1
10	62	64	0.25	0.27	0.52	1	1	1
11	70	74	0.17	0.38	0.55	7	14	4
12	70	95	0.59	0.26	0.85	7	21	5
13	74	94	0.034	0.64	0.68	14	7	4
14	78	90	0.46	0.38	0.84	1	1	1
15	81	93	0.27	0.31	0.58	1	1	1
16	81	98	0.27	0.33	0.61	1	1	1
17	82	91	0.045	0.92	0.96	15	29	9
18	89	184	0.24	0.5	0.74	2	6	2
19	91	119	0.22	0.67	0.89	29	12	8
20	93	98	0.31	0.3	0.61	1	1	1
21	94	155	0.28	0.29	0.57	7	2	2
22	103	233	0.4	0.13	0.53	4	3	2
23	135	154	0.4	0.43	0.82	1	1	1