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. 2022 Jun 22;12:10499. doi: 10.1038/s41598-022-14531-0

Table 2.

The presence of HCBS in different subtypes of SCA and MSA-C.

Total Length of the expanded CAG repeats HCBS negative (n = 400, 58.48%) HCBS positive (n = 284, 41.52%) p value
N Mean ± SD (N) N % N %
SCA 1 25 46.88 ± 4.67 (25) 24.00 96.00 1.00 4.00 < 0.001
SCA 2 68 41.35 ± 3.94 (68) 48.00 70.59 20.00 29.41
SCA 3 253 70.64 ± 4.26 (253) 246.00 97.23 7.00 2.77
SCA 6 34 23.35 ± 1.28 (34) 34.00 100.00 0.00 0
SCA 17 18 44.81 ± 3.02 (18) 17.00 94.44 1.00 5.56
MSA-C 286 0 31 10.84 255 89.16

HCBS hot cross bun sign; MSA-C multiple system atrophy, cerebellar type; SCA spinocerebellar ataxia.

Chi-square test.

Numeric data are presented as mean ± standard deviation.