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. 2022 Jun 22;12:10547. doi: 10.1038/s41598-022-14954-9

Table 1.

Demographics and clinical features.

All RA (N = 166) Without CAC (N = 79) With CAC (N = 82) P value
Age, years 54 [45, 63] 48 [40, 54] 60 [54, 69]  < 0.001
Sex, # female 114 (69) 64 (81) 47 (57) 0.001
Race, # Caucasian 150 (88) 68 (86) 75 (91) 0.28
DAS28-ESR, score 3.88 [2.64,3.4.84] 3.46 [2.39, 4.40] 4.05 [2.84, 5.01] 0.04
Rheumatoid factor, # positive 114 (72) 52 (69) 58 (72) 0.66
hs-CRP, mg/dl 4.0 [1.2, 11] 3.00 [1.00, 9.50] 5.00 [2.00, 12.50] 0.09
Waist/hip ratio, units 0.88 [0.81, 0.95] 0.84 [0.78, 0.92] 0.91 [0.83, 0.99]  < 0.001
Body Mass Index, kg/m2 28.3 [24.0, 33.1] 28.30 [24.02, 33.51] 28.34 [23.71, 31.53] 0.34
Systolic BP, mmHg 133 [118, 146] 129 [116, 139] 137 [121, 151] 0.004
Diastolic BP, mmHg 75 [67, 82] 73 [67, 80] 76 [69, 85] 0.13
Current smoker, # yes 40 (24) 17 (22) 22 (27) 0.44
Total cholesterol, mg/dL 184 [156, 210] 183 [157, 204] 188 [154, 214] 0.70
LDL-cholesterol, mg/dL 111 [88, 134] 105 [89, 134] 115 [90, 136] 0.44
HDL-cholesterol, mg/dL 43 [37, 54] 44 [38, 55] 43 [36, 53] 0.32
Triglycerides, mg/dL 111 [80, 158] 108 [81, 149] 112 [80, 164] 0.58
CAC score, Agatston units 2.70 [0.00, 150.30] 0.00 [0.00, 0.00] 148.80 [40.80, 470.30]  < 0.001
Statins, # user 21 (12) 6 (7) 15 (18) 0.04
NSAIDs, # user 54 (33) 29 (37) 25 (30) 0.40
Corticosteroid, # user 89 (54) 42 (53) 45 (55) 0.83
Methotrexate, # user 118 (72) 61 (77) 54 (66) 0.11
Hydroxychloroquine, # user 42 (25) 23 (29) 17 (21) 0.22
Leflunomide, # user 29 (18) 13 (16) 16 (20) 0.61
Anti-TNFα, # user 33 (20) 17 (22) 14 (17) 0.47