Table 1.
Demographics and clinical features.
| All RA (N = 166) | Without CAC (N = 79) | With CAC (N = 82) | P value | |
|---|---|---|---|---|
| Age, years | 54 [45, 63] | 48 [40, 54] | 60 [54, 69] | < 0.001 |
| Sex, # female | 114 (69) | 64 (81) | 47 (57) | 0.001 |
| Race, # Caucasian | 150 (88) | 68 (86) | 75 (91) | 0.28 |
| DAS28-ESR, score | 3.88 [2.64,3.4.84] | 3.46 [2.39, 4.40] | 4.05 [2.84, 5.01] | 0.04 |
| Rheumatoid factor, # positive | 114 (72) | 52 (69) | 58 (72) | 0.66 |
| hs-CRP, mg/dl | 4.0 [1.2, 11] | 3.00 [1.00, 9.50] | 5.00 [2.00, 12.50] | 0.09 |
| Waist/hip ratio, units | 0.88 [0.81, 0.95] | 0.84 [0.78, 0.92] | 0.91 [0.83, 0.99] | < 0.001 |
| Body Mass Index, kg/m2 | 28.3 [24.0, 33.1] | 28.30 [24.02, 33.51] | 28.34 [23.71, 31.53] | 0.34 |
| Systolic BP, mmHg | 133 [118, 146] | 129 [116, 139] | 137 [121, 151] | 0.004 |
| Diastolic BP, mmHg | 75 [67, 82] | 73 [67, 80] | 76 [69, 85] | 0.13 |
| Current smoker, # yes | 40 (24) | 17 (22) | 22 (27) | 0.44 |
| Total cholesterol, mg/dL | 184 [156, 210] | 183 [157, 204] | 188 [154, 214] | 0.70 |
| LDL-cholesterol, mg/dL | 111 [88, 134] | 105 [89, 134] | 115 [90, 136] | 0.44 |
| HDL-cholesterol, mg/dL | 43 [37, 54] | 44 [38, 55] | 43 [36, 53] | 0.32 |
| Triglycerides, mg/dL | 111 [80, 158] | 108 [81, 149] | 112 [80, 164] | 0.58 |
| CAC score, Agatston units | 2.70 [0.00, 150.30] | 0.00 [0.00, 0.00] | 148.80 [40.80, 470.30] | < 0.001 |
| Statins, # user | 21 (12) | 6 (7) | 15 (18) | 0.04 |
| NSAIDs, # user | 54 (33) | 29 (37) | 25 (30) | 0.40 |
| Corticosteroid, # user | 89 (54) | 42 (53) | 45 (55) | 0.83 |
| Methotrexate, # user | 118 (72) | 61 (77) | 54 (66) | 0.11 |
| Hydroxychloroquine, # user | 42 (25) | 23 (29) | 17 (21) | 0.22 |
| Leflunomide, # user | 29 (18) | 13 (16) | 16 (20) | 0.61 |
| Anti-TNFα, # user | 33 (20) | 17 (22) | 14 (17) | 0.47 |