Table 1.
ABPM parameters: comparison between patients with and without autonomic failure
| Ambulatory blood pressure monitoring | ||||
|---|---|---|---|---|
| AF− (n. 51) | AF+ (n. 29) | P value | ||
| Age (years) (mean ± SD) | 61 ± 10 | 67 ± 10 | < 0.01 | |
| Disease duration (years) (mean ± SD) | 5.5 ± 3 | 7 ± 4.5 | 0.08 | |
| LEDD (mg) (mean ± SD) | 657 ± 326 | 694 ± 403 | 0.72 | |
| Female sex [n (%)] | 17 (33) | 9 (31) | 0.08 | |
| Daytime SBP (mmHg) (mean ± SD) | 122 ± 10 | 118 ± 8 | 0.04 | |
| Daytime MBP (mmHg) (mean ± SD) | 91 ± 9 | 88 ± 7 | 0.24 | |
| Daytime DBP (mmHg) (mean ± SD) | 75 ± 9 | 73 ± 7 | 0.13 | |
| Night-time SBP (mmHg) (mean ± SD) | 109 ± 11 | 122 ± 17 | < 0.01 | |
| Night-time MBP (mmHg) (mean ± SD) | 79 ± 8 | 89 ± 14 | < 0.01 | |
| Night-time DBP (mmHg) (mean ± SD) | 64 ± 8 | 71 ± 13 | < 0.01 | |
| Daytime SBP loads (%) (mean ± SD) | 19 ± 20 | 15 ± 11 | 0.19 | |
| Daytime DBP loads (%) (mean ± SD) | 17 ± 22 | 18 ± 15 | 0.83 | |
| Night-time SBP loads (%) (mean ± SD) | 19 ± 24 | 46 ± 36 | < 0.01 | |
| Night-time DBP loads (%) (mean ± SD) | 23 ± 25 | 45 ± 37 | < 0.01 | |
| Reverse dipping pattern [n (%)] | 5 (10) | 17 (58) | < 0.01 | |
| w-BPV > 11 mmHg [n (%)] | 25 (49) | 20 (68) | 0.08 | |
| SD-daytime SBP > 16 mmHg [n (%)] | 4 (8) | 10 (34) | 0.02 | |
| PPH [n (%)] | 23 (46) | 17 (58) | 0.27 | |
| Hypo-aw Δ15/24h [n (%)] | 4 (8) | 13 (44) | < 0.01 | |
| Hypo-ep Δ15/24h (n.) (mean ± SD) | 0.4 ± 0.6 | 3.4 ± 3.3 | < 0.01 | |
AF autonomic failure, LEDD levodopa equivalent daily dose, SBP systolic blood pressure, MBP mean blood pressure, DBP diastolic blood pressure, w-BPV weighted blood pressure variability, SD-daytime SBP standard deviation of diurnal systolic blood pressure, PPH post-prandial hypotension, Hypo-awΔ15/24h awakening hypotension, Hypo-epΔ15/24h hypotensive episodes