Table 3.
Univariate and multivariate logistic regression analysis
| A | Outcome | ||
|---|---|---|---|
| ABPM predictive Variables (categorical) |
Autonomic failure | ||
| Univariate analysis (IC 95%) | Multivariate analysis (IC 95%) | ||
| Hypo-awΔ15/24h | OR | 9.1 (2.6–32) | 8.7 (2–37.4) |
| P value | < 0.01 | 0.01 | |
| ≥ 3 Hypo-epΔ15/24h | OR | 40.2 (5.8–78) | 60.7 (12.1–108) |
| P value | < 0.01 | < 0.01 | |
| PPH | OR | 1.6 (0.7–4.2) | 1.4 (0.4–4.5) |
| P value | 0.28 | 0.57 | |
| Reverse dipping | OR | 13 (4–42) | 16.6 (3.2–87) |
| P value | < 0.01 | < 0.01 | |
| w-BPV (> 11 mmHg) | OR | 2.3 (0.9–6) | 1.4 (0.5–4.3) |
| P value | 0.09 | 0.57 | |
| DS daytime SBP (> 16 mmHg) | OR | 6.1 (1.7–22.1) | 3.8 (0.9–16) |
| P value | < 0.01 | 0.06 | |
| B | Outcome | ||
|---|---|---|---|
| ABPM predictive Variables (continuous) |
Autonomic failure | ||
| Univariate analysis (IC 95%) | Multivariate analysis (IC 95%) | ||
| Diurnal SBP | OR | 0.95 (0.9–1.01) | 0.95 (0.89–1.01) |
| P value | 0.06 | 0.06 | |
| Diurnal MBP | OR | 0.96 (0.9–1.01) | 0.96 (0.89–1.03) |
| P value | 0.14 | 0.24 | |
| Diurnal DBP | OR | 0.97 (0.91–1.02) | 0.97 (0.91–1.04) |
| P value | 0.24 | 0.41 | |
| Nocturnal SBP | OR | 1.07 (1.03–1.11) | 1.06 (1.01–1.12) |
| P value | < 0.01 | 0.01 | |
| Nocturnal MBP | OR | 1.09 (1.04–1.15) | 1.08 (1.02–1.15) |
| P value | < 0.01 | 0.01 | |
| Nocturnal DBP | OR | 1.08 (1.03–1.14) | 1.07 (1.01–1.13) |
| P value | < 0.01 | 0.03 | |
Autonomic failure (AF+) was used as dependent variable (outcome). In univariate analysis, the independent variables were Hypo-awΔ15/24h (awakening hypotension), ≥ 3 Hypo-epΔ15/24h (hypotensive episodes), reverse dipping, w-BPV (weighted blood pressure variability), DS-daytime SBP (standard deviation of daytime systolic blood pressure), diurnal and nocturnal SBP (systolic blood pressure), diurnal and nocturnal MBP (mean blood pressure), diurnal and nocturnal DBP (diastolic blood pressure). In multivariate analysis age, sex, disease duration and LEDD (levodopa equivalent daily dose) were used as potential confounding variables