Table 2.

Characteristics of LISEN patients with local recurrence (LR), regional recurrence (RR), distant metastasis (DM) and death

Pts	Age	Pathological Stage		G	Molecular Subtype	HER‑2	Ki67 (in %)	LR	RR	DM Site and timing	Death
1	41	T1c	N1a	G1	Luminal B	Positive	30	Yes	No	No	No
2	42	T1c	N1mic	G1	Luminal A	Negative	5	Yes	No	No	No
3	45	T2	N1mic	G2	Luminal B	Negative	70	Yes	Yes (S)	Bone (M)	No
4	47	T1c	N1a	G1	Luminal A	Negative	20	No	No	Bone, liver, lung	No
5	48	T1b	N1a	G2	Luminal B	Negative	40	Yes	No	Bone (M)	No
6	49	T1c	N1a	G2	Luminal B	Negative	60	No	No	Bone	Yes
7	56	T2	N1a	G1	Luminal B	Positive	12	No	No	Bone	No

pts patients, G grading, DM distant metastases, LR local recurrence, RR regional recurrence, S synchronous, M metachronous