Table 3.

Risk of bias of individual trials

Study ID	Intervention	Comparator	Outcome	Randomisation process	Deviations from intended interventions	Missing outcome data	Measurement of outcome	Selection of reported result	Overall
[15]	IV lorazepam	IV diazepam, IV placebo	Objective	+	+	+	+	+	+
[15]	IV lorazepam	IV diazepam, IV placebo	Subjective	+	+	+	+	+	+
[21]	IV levetiracetam + clonazepam	IV placebo + clonazepam	Objective	+	+	+	+	+	+
[21]	IV levetiracetam + clonazepam	IV placebo + clonazepam	Subjective	+	+	+	+	+	+
[23]	IV phenobarbital + phenytoin	IV diazepam + phenytoin	Objective	?	?	+	+	?	?
[23]	IV phenobarbital + phenytoin	IV diazepam + phenytoin	Subjective	?	?	+	−	?	−
[22]	IM midazolam	IV lorazepam	Objective	+	+	+	+	+	+
[22]	IM midazolam	IV lorazepam	Subjective	+	+	+	+	+	+

 + Low risk; ? Some concerns; − High risk; IM: intramuscular; IV: intravenous