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. 2022 Apr 7;129(7):945–959. doi: 10.1007/s00702-022-02483-8

Table 2.

Characteristics of limited study population (n = 27)

Characteristics of limited study population (n = 27)
Serum concentrations, n 27
Patients, n 27
Gender, n (%)
  Male 26 (96.3)
  Female 1 (3.7)
Age (years), n = 27, mean ± SD (min–max) 12 ± 3.4 (8–21)
  Children ≤ 12 years, n (%) 14 (51.9)
  Adolescents > 12 years, n (%) 13 (48.1)
Weight (kg), n = 27, mean ± SD (min–max) 49.5 ± 20.2 (21.9–85)
Nicotine abuse, n (%) 3 (11.1)
Oral contraception, n (%) 0 (0)
Dose (mg/day), n = 27, mean ± SD (min–max) 48.2 ± 19.4 (10–80)
Weight-normalized dose (mg/(kg x day)), n = 27, mean ± SD (min–max) 1.0 ± 0.3 (0.3–1.6)
Patients with ICD-10 diagnosis, n (%) 20
  Attention deficit hyperactivity disorder, predominantly inattentive type (F90.0) 8 (40)
  Attention deficit hyperactivity disorder, predominantly hyperactive type (F90.1) 10 (50)
  Combined vocal and multiple motor tic disorder (F95.2) 2 (10)
Patients with comorbidities, n (%) 12
  One comorbidity 10 (83.3)
  More than one comorbidity 2 (16.7)
Comorbidities, n, multiple entries
  Undifferentiated schizophrenia (F20.3) 1
  Major depressive disorder, moderate (F32.1) 1
  Anorexia nervosa (F50.0) 1
  Sleep terrors (F51.4) 1
  Specific reading disorder (F81.0) 3
  Specific developmental disorder of motor function (F82.9) 1
  Atypical autistic disorder (F84.1) 1
  Other mixed disorders of conduct and emotions (F92.8) 2
  Other childhood emotional disorders (F93.8) 2
  Childhood emotional disorder, unspecified (F93.9) 1
Patients with comedication, n (%) 7
  One comedication 6 (85.7)
  More than one comedication 1 (14.3)
Comedication, n (%), multiple entries
  Clozapine 1 (12.5)
  Methylphenidate 2 (25)
  Olanzapine 1 (12.5)
  Pipamperone 1 (12.5)
  Risperidone 2 (25)
  Sodium valproate 1 (12.5)

SD standard deviation, min minimum, max maximum, ICD-10 International statistical classification of diseases and related health problems