Table 2.
Characteristics of limited study population (n = 27)
Characteristics of limited study population (n = 27) | ||
---|---|---|
Serum concentrations, n | 27 | |
Patients, n | 27 | |
Gender, n (%) | ||
Male | 26 | (96.3) |
Female | 1 | (3.7) |
Age (years), n = 27, mean ± SD (min–max) | 12 ± 3.4 | (8–21) |
Children ≤ 12 years, n (%) | 14 | (51.9) |
Adolescents > 12 years, n (%) | 13 | (48.1) |
Weight (kg), n = 27, mean ± SD (min–max) | 49.5 ± 20.2 | (21.9–85) |
Nicotine abuse, n (%) | 3 | (11.1) |
Oral contraception, n (%) | 0 | (0) |
Dose (mg/day), n = 27, mean ± SD (min–max) | 48.2 ± 19.4 | (10–80) |
Weight-normalized dose (mg/(kg x day)), n = 27, mean ± SD (min–max) | 1.0 ± 0.3 | (0.3–1.6) |
Patients with ICD-10 diagnosis, n (%) | 20 | |
Attention deficit hyperactivity disorder, predominantly inattentive type (F90.0) | 8 | (40) |
Attention deficit hyperactivity disorder, predominantly hyperactive type (F90.1) | 10 | (50) |
Combined vocal and multiple motor tic disorder (F95.2) | 2 | (10) |
Patients with comorbidities, n (%) | 12 | |
One comorbidity | 10 | (83.3) |
More than one comorbidity | 2 | (16.7) |
Comorbidities, n, multiple entries | ||
Undifferentiated schizophrenia (F20.3) | 1 | |
Major depressive disorder, moderate (F32.1) | 1 | |
Anorexia nervosa (F50.0) | 1 | |
Sleep terrors (F51.4) | 1 | |
Specific reading disorder (F81.0) | 3 | |
Specific developmental disorder of motor function (F82.9) | 1 | |
Atypical autistic disorder (F84.1) | 1 | |
Other mixed disorders of conduct and emotions (F92.8) | 2 | |
Other childhood emotional disorders (F93.8) | 2 | |
Childhood emotional disorder, unspecified (F93.9) | 1 | |
Patients with comedication, n (%) | 7 | |
One comedication | 6 | (85.7) |
More than one comedication | 1 | (14.3) |
Comedication, n (%), multiple entries | ||
Clozapine | 1 | (12.5) |
Methylphenidate | 2 | (25) |
Olanzapine | 1 | (12.5) |
Pipamperone | 1 | (12.5) |
Risperidone | 2 | (25) |
Sodium valproate | 1 | (12.5) |
SD standard deviation, min minimum, max maximum, ICD-10 International statistical classification of diseases and related health problems