. 2022 May 23;96(8):2361–2380. doi: 10.1007/s00204-022-03309-y

Table 2.

Descriptive statistic of the kinetic constants V_max, K_m and catalytic efficiencies for R-EDDP and S-EDDP formation by 25 Caucasian and 25 Chinese individual human liver microsomes

	Caucasian individuals						Chinese individuals
	R-EDDP formation			S-EDDP formation			R-EDDP formation			S-EDDP formation
	V_max^a	K_m^b	Catalytic efficiency^c	V_max^a	K_m^b	Catalytic efficiency^c	V_max^a	K_m^b	Catalytic efficiency^c	V_max^a	K_m^b	Catalytic efficiency^c
Mean (μ_x)	0.40	155.1	2.87	0.34	111.3	4.27	0.064	127.7	0.55	0.046	115.6	0.47
SD^d	0.324	42.8	2.64	0.319	44.2	5.54	0.031	42.4	0.35	0.021	63.6	0.28
CV_x %^e	80.3	27.6	92.1	93.8	40	130	48.5	33.2	64.3	46.5	55	59.8
Fold-differences^f	13	3	19	17	4	37	11	4	10	11	8	12

^anmol/min/mg liver microsomes

^bµM

^cV_max/K_m, µl/min/mg protein

^dStandard deviation of kinetic constants

^eCoefficients of variation, % (= SD/mean × 100)

^fHighest/lowest values