Table 1.
Individual patient scores and mean data of involuntary movements (AIMS), dystonia and disability (BFMDRS-M/D) at BL, ST-FU, 4y-FU and LT-FU as well as individual ratings in mood and cognition validated by the BDI and MMSE in patients 1–5 or HAM-D and Mattis in patients 6 and 7 at BL and LT-FU (mean data given only for patients 1–5)
| Patient | LT-FU (years) | AIMS BL | AIMS ST-FU | AIMS 4y-FU | AIMS LT-FU | BFMDRS (M/D) ST-FU | BFMDRS (M/D) 4y-FU | BFMDRS (M/D) LT-FU | BDI or HAM-Da (BL/LT-FU) | MMSE or Mattisb (BL/LT-FU) |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 14 | 19 | 3 | 4 | 5 | 8/3 | 9/1 | 4/1 | 18/5 | 29/28 |
| 2 | 12 | 20 | 3 | 4 | 5 | 2/3 | 3/3 | 3/1 | 12/3 | 27/28 |
| 3 | 12 | 33 | 6 | 0 | 5 | 15/0 | 0/0 | 4.5/1 | 3/3 | 28/28 |
| 4 | 10 | 15 | 11 | 10 | 8 | 16/5 | 13/8 | 3.5/3 | 21/5 | 27/28 |
| 5 | 10 | 24 | 4 | 5 | 4 | 6/0 | 5/3 | 2.5/0 | 20/11 | 27/25 |
| 6 | 8 | 11 | 0 | 5 | 4 | 4/1 | 4.5/0 | 4.5/0 | 13a/0a | 140b/142b |
| 7 | 5 | 25 | 1 | 0 | 5 | 0/0 | 4/0 | 2/0 | 17a/7a | 144b/144b |
| Mean ± SD | 10 ± 3.0 | 22 ± 8.7 | 4 ± 3.7 | 4 ± 3.4 | 5 ± 1.3 | 7 ± 6.1/2 ± 2.0 | 6 ± 4.6/2 ± 2.9 | 3 ± 1.0/1 ± 1.1 | 14.8 ± 6.7/5.4 ± 3.0 |
AIMS Abnormal Involuntary Movement Scale, BFMDRS Burke–Fahn–Marsden Dystonia Scale for motor impairment (M) and degree of disability (D), BDI Beck depression inventory, MMSE Mini-Mental State Exam, HAM-D Hamilton depression rating scale, Mattis Mattis dementia rating scale, BL baseline, ST-FU short-term follow-up, 4y-FU 4 year-follow-up, LT-FU long-term follow-up
HAM-D-values are marked with a and Mattis values are marked with b, respectively