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. 2022 Jun 22;12:10567. doi: 10.1038/s41598-022-14575-2

Table 1.

The relationship between the expression of NTN4 and clinicopathological data.

Characteristic NTN4 mRNA P
Low(n = 541) High(n = 542)
Age (years) 0.035
Median (IQR) 57 (48, 66) 60 (49, 68) 0.012
 <  = 60 318 (29.4%) 283 (26.1%)
 > 60 223 (20.6%) 259 (23.9%)
T stage, n (%)  < 0.001
T1 113 (10.5%) 164 (15.2%)
T2 349 (32.3%) 280 (25.9%)
T3 60 (5.6%) 79 (7.3%)
T4 17 (1.6%) 18 (1.7%)
N stage, n (%) 0.653
N0 258 (24.2%) 256 (24.1%)
N1 179 (16.8%) 179 (16.8%)
N2 61 (5.7%) 55 (5.2%)
N3 33 (3.1%) 43 (4%)
M stage, n (%) 1.000
M0 452 (49%) 450 (48.8%)
M1 10 (1.1%) 10 (1.1%)
Menopause status, n (%) 0.916
Pre 117 (12%) 112 (11.5%)
Peri 20 (2.1%) 20 (2.1%)
Post 348 (35.8%) 355 (36.5%)
Histological type, n (%)  < 0.001
Infiltrating Ductal Carcinoma 440 (45%) 332 (34%)
Infiltrating Lobular Carcinoma 52 (5.3%) 153 (15.7%)
Pathologic stage, n (%) 0.004
Stage I 71 (6.7%) 110 (10.4%)
Stage II 335 (31.6%) 284 (26.8%)
Stage III 117 (11%) 125 (11.8%)
Stage IV 8 (0.8%) 10 (0.9%)
PR status, n (%)  < 0.001
Negative 267 (25.8%) 75 (7.3%)
Indeterminate 3 (0.3%) 1 (0.1%)
Positive 245 (23.7%) 443 (42.8%)
ER status, n (%)  < 0.001
Negative 202 (19.5%) 38 (3.7%)
Indeterminate 1 (0.1%) 1 (0.1%)
Positive 313 (30.2%) 480 (46.4%)
HER2 status, n (%) 0.438
Negative 264 (36.3%) 294 (40.4%)
Indeterminate 7 (1%) 5 (0.7%)
Positive 82 (11.3%) 75 (10.3%)

IQR interquartile range.