Table 5.
Caenorhabditis elegans SIN-3 protein interactors containing LxxLL motifs. LxxLL motif is an acidic leucine (L)–rich protein binding motif used by proteins to interact with the PAH1 domain of SIN3 protein. The protein sequences were obtained from NCBI protein and Uniprot databases, and the motifs were scanned using the ScanProsite106 tool.
| Gene name | Accession no. | No. of LxxLL motifs | Name of the LXXLL motif |
|---|---|---|---|
| sin-3 | A5JYW9.1 | 2 | LgkLL, LmtLL |
| sir-2.1 | NP_001255484.1 | 1 | LsdLL |
| ceh-62 | Q09602.1 | 1 | LrlLL |
| f57c9.4 | NP_491459.1 | 1 | LpnLL |
| mab-3 | CAB16489.1 | 1 | LasLL |
| ztf-2 | CAA95789.1 | 1 | LasLL |
| wbgene00017431 | CCD69466.1 | 1 | LryLL |
| ets-5 | CCJ09391.1 | 1 | LleLL |
| nhr-43 | CDR32746.1 | 1 | LenLL |
| akt-1 | NP_001023646.1 | 2 | LenLL, LtgLL |
| ces-2 | CAB05032.1 | 1 | LrfLL |
| imb-3 | CCD67936.1 | 2 | LetLL, LvcLL |
| fkh-7 | CCD67108.1 | 1 | LskLL |
| nhr-67 | Q9XVV3.1 | 1 | LnfLL |
| lin-15a | Q27365.1 | 2 | LvaLL, LneLL |
| t04h1.2 | CAB01578.1 | 1 | LrtLL |
| nurf-1 | CAA0059157.1 | 4 | LvvLL, LyqLL, LleLL, LelLL |
| bar-1 | AAC17424.1 | 6 | LrdLL, LlmLL, LanLL, LksLL, LhkLL, LslLL |
| eyg-1 | NP_496116.1 | 1 | LslLL |
| akt-2 | CAA20936.1 | 2 | LenLL, LsgLL |
| gei-13 | CAA80171.2 | 2 | LaaLL, LnaLL |
| ztf-11 | CAB05737.2 | 1 | LmsLL |