Table 3.
Results from Cox regression model analysis.╫
Data ID | M-1, TRS | M-2, CPFs | M-3, TRS + CPFs | ||||||
---|---|---|---|---|---|---|---|---|---|
R2 | BIC¶ | p-value | R2 | BIC | p-value | R2 | BIC | p-value | |
TCGA-PRAD | 0.43 | 475.18 | 1.1 × 10–10 | 0.44 | 421.18 | 5.8 × 10–7 | 0.63 | 403.45 | 2.2 × 10–11 |
GSE54460 | 0.12 | 417.59 | 5.8 × 10–4 | 0.16 | 429.32 | 7.5 × 10–3 | 0.23 | 426.79 | 7.6 × 10–4 |
GSE84042 | 0.36 | 99.29 | 2.2 × 10–3 | 0.17 | 109.63 | 2.6 × 10–1 | 0.51 | 104.67 | 1.3 × 10–2 |
GSE21032 | 0.09 | 205.6 | 7.4 × 10–3 | 0.58 | 192.68 | 8.5 × 10–9 | 0.58 | 195.52 | 2.1 × 10–8 |
GSE70768 | 0.60 | 126.27 | 9.2 × 10–8 | 0.41 | 143.26 | 1.9 × 10–3 | 0.72 | 130.37 | 9.8 × 10–8 |
GSE70769 | 0.09 | 327.67 | 9.0 × 10–3 | 0.17 | 308.64 | 9.9 × 10–3 | 0.25 | 306.2 | 1.2 × 10–3 |
╫The three models (M-1, M-2 and M-3) are specified by the included predictor variable(s) for cancer relapse-free survival. TRS: transcriptomic risk score. CPFs: clinicopathologic prognostic factors. See the main text for a more detailed description.
¶BIC: Bayesian Information Criterion.