Table 2.
Relationship between the HDAC6 intensity level and clinicopathologic parameters of patients with OSCC.
| Clinicopathological parameter | HDAC 6 Intensity | |||
|---|---|---|---|---|
| Low | High | R | P-value | |
| Stage | − 0.12 | 0.891 | ||
| I/II | 40 | 39 | ||
| III/IV | 28 | 26 | ||
| Grade | 0.182 | 0.036 | ||
| 1 | 36 | 24 | ||
| 2 | 32 | 39 | ||
| 3 | 0 | 2 | ||
| Tumor size | − 0.14% | 0.874 | ||
| > 4 cm | 59 | 57 | ||
| < 4 cm | 9 | 8 | ||
| T stage | − 0.21 | 0.808 | ||
| I/II | 50 | 49 | ||
| III/IV | 18 | 16 | ||
| N stage | 0.83 | 0.342 | ||
| I/II | 54 | 47 | ||
| III/IV | 14 | 18 | ||
| M stage | − 0.85 | 0.33 | ||
| I/II | 67 | 65 | ||
| III/IV | 1 | 0 | ||
| Recurrence status | 0.101 | 0.246 | ||
| Negative | 55 | 47 | ||
| Positive | 13 | 18 | ||
| Metastasis status | 0.121 | 0.167 | ||
| Negative | 65 | 58 | ||
| Positive | 3 | 7 | ||