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. 2022 Jun 22;12:259. doi: 10.1038/s41398-022-02022-9

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — A Symptom groups, polygenic factors, and environmental risk factors are represented with different colors; bridge nodes are depicted with a diamond shape. Edges (lines) can be interpreted as partial correlations, with edge thickness representing the strength of the correlation. Blue edges represent positive associations; red edges represent negative associations. B Centrality indices and bridge expected influence index for Step-2 network. Anh = anhedonia; Cnc = difficulty concentrating; Com = beliefs in unreal communications; Con = beliefs in unreal conspiracy against self; Dea = thoughts of death; Dei = depression impairment; Gre = greenspace; IMD = Index of Multiple Deprivation; Pol = air pollution; PRd = depression PRS; PRs = schizophrenia PRS; Psi = psychosis impairment; Sad = feelings of sadness/depression; Sle = sleep changes; Tir = feelings of tiredness; Trau = cumulative trauma; Vis = seeing unreal visions; Voi = hearing unreal voices; Wei = weight change; Wor = feelings of worthlessness.