Table 1.
Summary of demographics, clinical characteristics and image dataset information stratified by disease.
| Disease | Total number of scans | Number of patients | Number of HP gas scans | Sex* | Median (range) age* | Mean ± SD ventilated lung volume (liters)* | ||
|---|---|---|---|---|---|---|---|---|
| 3He | 129Xe | Male | Female | |||||
| Healthy | 43 | 33 | 1 | 42 | 15 | 13 | 12 (9, 76) | 3.78 ± 1.18 |
| Asthma | 169 | 81 | 4 | 165 | 28 | 52 | 50 (13, 73) | 4.23 ± 1.03 |
| Asthma/COPD overlap | 11 | 5 | 0 | 11 | 0 | 5 | 56 (45, 67) | 4.13 ± 0.68 |
| Bronchiectasis | 3 | 3 | 1 | 2 | 1 | 1 | 15 (9, 29) | 3.76 ± 1.00 |
| CF | 247 | 58 | 134 | 113 | 29 | 28 | 16 (6, 48) | 3.65 ± 1.05 |
| COPD | 62 | 23 | 56 | 6 | 4 | 5 | 64 (52, 80) | 4.43 ± 0.71 |
| Non-IPF ILD** | 77 | 41 | 0 | 77 | 25 | 16 | 69 (39, 83) | 3.78 ± 0.80 |
| Investigation for possible airways disease | 38 | 21 | 5 | 33 | 2 | 16 | 49 (36, 69) | 3.89 ± 1.05 |
| IPF | 46 | 20 | 45 | 1 | 17 | 3 | 72 (52, 80) | 3.87 ± 0.71 |
| Lung cancer | 22 | 16 | 14 | 8 | 10 | 6 | 69 (34, 85) | 4.12 ± 0.86 |
| Preterm birth | 41 | 40 | 4 | 37 | 15 | 25 | 12 (9, 14) | 2.75 ± 0.55 |
HP hyperpolarized, CF cystic fibrosis, COPD chronic obstructive pulmonary disease, ILD interstitial lung disease, IPF idiopathic pulmonary fibrosis, SD standard deviation.
*Data for 25 patients was unavailable.
**Contains connective tissue disease-associated ILD (CTD-ILD), hypersensitivity pneumonitis and drug-induced ILD (DI-ILD).