Hammerhead ribozyme type II scheme
(A) Model hammerhead ribozyme secondary structure. (B) Possible tertiary interactions between loop L2 and stem I are enabled in the Y conformation. The target sequence is marked in green, with the black arrow indicating the cleavage site. Two nucleosides, 2.2 and 2.3, of tetraloop L2 are marked in yellow. Only the sequence of the conserved catalytic core and target NUH are shown.