Skip to main content
. Author manuscript; available in PMC: 2024 Jul 1.
Published in final edited form as: Mass Spectrom Rev. 2021 Dec 23;42(4):1332–1357. doi: 10.1002/mas.21766

Scheme 2.

Scheme 2.

Characteristic fragment series generated by gas-phase activation of NA precursor ions. Typical a-B fragments are generated by the concomitant loss of nucleobase and cleavage of the 3’ C-O bond. B corresponds to any nucleobase. R corresponds to H in deoxyribo-ONs; OH in ribo-ONs; and CH3O in 2’O-methyl-ribo-ONs. X corresponds to OH in deoxyribo- and ribo-ONs; SH in phosphorothioate-ONs; and CH3 in methylphosphonate-ONs.