Table 1.

Associations between antibody levels and risk of P. falciparum clinical malaria.

		Unadjusted PPE (1,000 parasites/µl)				Unadjusted PPE (2,500 parasites/µl)				Unadjusted PPE (5,000 parasites/µl)
Product ID	GeneID*	PPE %	Lower 95%CI	Upper 95%CI	P value**	PPE %	Lower 95%CI	Upper 95%CI	P value**	PPE %	Lower 95%CI	Upper 95%CI	P value**
DC150	PF3D7_0733000_DBLα0.16	1.000	0.990	1.000	0.001	1.000	0.990	1.000	0.001	1.000	0.990	1.000	0.001
RS23	PF3D7_0201000	0.819	0.230	0.957	0.021	0.806	0.174	0.954	0.027	0.817	0.218	0.957	0.022
DC54	PF3D7_0420700_DBLα0.1	0.735	0.114	0.921	0.031	0.716	0.046	0.915	0.042	0.730	0.089	0.920	0.035
DC72	PF3D7_0425800_DBLβ3	0.727	0.087	0.918	0.035	0.707	0.017	0.913	0.047	0.714	0.035	0.915	0.044
DC21	PF3D7_0300100_CIDRβ1	0.720	0.184	0.904	0.020	0.698	0.117	0.897	0.029	0.698	0.111	0.898	0.030
DC266	PF3D7_1300300_DBLγ12	0.705	0.139	0.899	0.026	0.681	0.066	0.891	0.037	0.711	0.148	0.902	0.024
DC251	PF3D7_1240600_DBLα0.20	0.702	0.004	0.911	0.049	0.680	(0.072)	0.905	0.065	0.705	0.005	0.913	0.049
RS89	PF3D7_0700200	0.700	(0.002)	0.910	0.050	0.679	(0.076)	0.904	0.066	0.708	0.015	0.914	0.047
5400	PF3D7_1035400	0.698	0.275	0.874	0.007	0.658	0.175	0.859	0.017	0.592	0.009	0.832	0.048
DC169	PF3D7_0800300_DBLδ1	0.695	0.268	0.873	0.008	0.655	0.167	0.857	0.018	0.650	0.148	0.856	0.021
DC110	PF3D7_0632500_DBLδ4	0.691	0.259	0.871	0.008	0.651	0.157	0.855	0.019	0.668	0.191	0.864	0.015
DC73	PF3D7_0425800_DBLβ3	0.691	0.259	0.871	0.009	0.660	0.179	0.859	0.016	0.672	0.201	0.866	0.014
DC119	PF3D7_0700100_CIDRα3.1	0.691	0.259	0.871	0.009	0.660	0.179	0.859	0.016	0.655	0.160	0.858	0.019
DC242	PF3D7_1240300_DBLα0.7	0.691	0.098	0.894	0.032	0.667	0.024	0.886	0.045	0.663	0.007	0.885	0.049
DC239	PF3D7_1219300_CIDRα3.4	0.684	0.078	0.891	0.035	0.659	0.001	0.883	0.050	0.678	0.051	0.890	0.040
DC137	PF3D7_0712400_DBLγ9	0.681	0.151	0.881	0.022	0.655	0.074	0.871	0.035	0.669	0.108	0.878	0.029
DC118	PF3D7_0700100_DBLα0.1	0.677	0.139	0.879	0.024	0.650	0.061	0.869	0.037	0.679	0.135	0.881	0.025
DC102	PF3D7_0617400_CIDRα2.1	0.666	0.200	0.861	0.014	0.634	0.115	0.848	0.026	0.696	0.259	0.875	0.009
DC18	PF3D7_0300100_DBLα0.9	0.660	0.008	0.883	0.048	0.633	(0.073)	0.875	0.067	0.643	(0.050)	0.879	0.061
DC158	PF3D7_0800100_CIDRβ1	0.657	0.140	0.863	0.023	0.616	0.032	0.848	0.043	0.636	0.073	0.857	0.034
DC260	PF3D7_1300100_CIDRα2.4	0.652	(0.014)	0.881	0.053	0.624	(0.100)	0.872	0.074	0.641	(0.059)	0.878	0.063
DC175	PF3D7_0808700_DBLα0.2	0.648	(0.027)	0.879	0.056	0.621	(0.110)	0.870	0.077	0.607	(0.158)	0.866	0.090
DC99	PF3D7_0600400_DBLα1.3	0.644	0.051	0.867	0.039	0.615	(0.032)	0.856	0.058	0.621	(0.024)	0.860	0.056
DC49	PF3D7_0412900_CIDRγ2	0.622	0.094	0.842	0.029	0.586	0.001	0.829	0.050	0.609	0.045	0.840	0.039
DC157	PF3D7_0800100_DBLδ1	0.621	0.121	0.837	0.024	0.571	(0.004)	0.816	0.051	0.565	(0.028)	0.816	0.058
RS264	PF3D7_0113600	0.619	0.115	0.836	0.025	0.594	0.049	0.826	0.038	0.559	(0.041)	0.813	0.062
DC17	PF3D7_0223500_CIDRβ1	0.618	0.114	0.835	0.025	0.579	0.015	0.820	0.046	0.580	0.008	0.822	0.048
DC15	PF3D7_0223500_CIDRα3.4	0.613	0.102	0.833	0.027	0.573	0.002	0.817	0.050	0.522	(0.129)	0.798	0.092
DC64	PF3D7_0421100_DBLδ1	0.613	0.102	0.833	0.027	0.561	(0.026)	0.812	0.057	0.559	(0.040)	0.813	0.061
DC71	PF3D7_0425800_CIDRα1.6	0.612	0.101	0.833	0.027	0.571	(0.004)	0.816	0.051	0.558	(0.044)	0.813	0.063
DC46	PF3D7_0412900_DBLα0.1	0.611	0.097	0.832	0.028	0.569	(0.007)	0.816	0.052	0.601	0.057	0.831	0.036
WE35	PF3D7_1035900	0.610	0.095	0.832	0.028	0.673	0.209	0.864	0.013	0.687	0.236	0.872	0.011
RS163	PF3D7_1041100	0.610	0.095	0.832	0.028	0.585	0.031	0.823	0.042	0.579	0.007	0.822	0.048
RS158	PF3D7_1040600	0.610	0.095	0.832	0.028	0.585	0.031	0.823	0.042	0.577	0.001	0.821	0.050
DC23	PF3D7_0324900_CIDRα2.1	0.609	0.093	0.831	0.029	0.567	(0.013)	0.815	0.053	0.517	(0.139)	0.795	0.097
DC166	PF3D7_0800300_CIDRα1.6	0.608	0.092	0.831	0.029	0.556	(0.038)	0.810	0.061	0.568	(0.021)	0.817	0.056
DC36	PF3D7_0400400_DBLδ1	0.606	0.086	0.830	0.030	0.565	(0.018)	0.814	0.055	0.582	0.013	0.823	0.047
RS99	PF3D7_0732000	0.605	0.084	0.830	0.030	0.581	0.021	0.821	0.045	0.564	(0.029)	0.816	0.058
WE29	PF3D7_1028700	0.598	0.036	0.832	0.041	0.551	(0.085)	0.814	0.075	0.654	0.122	0.864	0.026
DC66	PF3D7_0421300_DBLα0.24	0.595	0.062	0.826	0.035	0.542	(0.072)	0.804	0.072	0.595	0.043	0.828	0.039
DC109	PF3D7_0632500_DBLγ1	0.594	0.059	0.825	0.036	0.541	(0.074)	0.804	0.073	0.550	(0.064)	0.809	0.069
DC232	PF3D7_1200600_DBLpam2	0.589	0.047	0.823	0.038	0.547	(0.058)	0.806	0.067	0.518	(0.137)	0.796	0.096
DC139	PF3D7_0712600_CIDRα3.1	0.586	0.007	0.827	0.048	0.534	(0.124)	0.807	0.089	0.441	(0.362)	0.771	0.200
DC30	PF3D7_0400100_CIDRβ1	0.571	0.005	0.815	0.049	0.527	(0.106)	0.798	0.084	0.525	(0.120)	0.799	0.089
DC19	PF3D7_0300100_CIDRα2.4	0.566	0.016	0.808	0.046	0.504	(0.134)	0.783	0.096	0.465	(0.240)	0.769	0.145
WE50.1	PF3D7_1035300	0.515	(0.097)	0.786	0.082	0.571	(0.004)	0.817	0.051	0.608	0.073	0.834	0.033
RS189	PF3D7_1254500	0.512	(0.105)	0.784	0.085	0.596	0.055	0.827	0.037	0.549	(0.065)	0.809	0.069
WE48	PF3D7_0707300	0.477	(0.185)	0.769	0.120	0.551	(0.051)	0.808	0.065	0.598	0.048	0.830	0.038
MSP10_1-1	PF3D7_0620400	0.477	(0.214)	0.774	0.131	0.558	(0.068)	0.817	0.070	0.593	0.009	0.833	0.048
WE27	PF3D7_0104200	(0.977)	(3.478)	0.127	0.102	(1.293)	(4.364)	0.019	0.056	(1.618)	(5.368)	(0.076)	0.034

*In bold are the proteins cross-selected by the three malaria definations.

**Yellow highlighted P values: statistically significant by the unadjusted analysis.