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. 2022 Jun 9;13:898139. doi: 10.3389/fendo.2022.898139

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Copyright © 2022 Torres Irizarry, Jiang, He and Xu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Adipose tissue distribution in humans and mice. White adipose tissue (WAT) is composed of unilocular white adipocytes characterized by a single large lipid droplet. Brown adipose tissue (BAT) consists of brown adipocytes with small lipid droplets and high mitochondrial density. White adipocytes can adopt brown-like morphology under cold exposure, increased SNS activity and β3-agonism, a process called WAT beiging. Adapted from (36). Figure 1 license number: XB23OHGTZA, Figure 2 license number: OZ23OHGU1X.