Table 3.
Various PRRs and their ligands.
| PRR | Ligand | Ref |
|---|---|---|
| TLR1 | Gram-positive bacterial components (triacyl lipopeptides, diacyl lipopeptides, GPI anchors, peptidoglycans, and lipoproteins) | (163) |
| TLR2* | Gram-positive bacterial components (peptidoglycans, lipopeptides, and lipoproteins) | (164) |
| TLR3* | Viral dsRNA | (165) |
| TLR4* | Gram-positive and gram-negative bacterial components (LPS, peptidoglycans, lipopeptides, and lipoproteins) | (166) |
| TLR5* | Flagellin of bacteria | (167) |
| TLR6* | Gram-positive bacterial components (triacyl lipopeptides, diacyl lipopeptides, GPI anchors, peptidoglycans, and lipoproteins) | (168) |
| TLR7 | Viral ssRNA and dsRNA | (169) |
| TLR8 | Viral and bacterial ssRNA and dsRNA degradation products | (170) |
| TLR9 | Unmethylated CpG DNA components | (171) |
| TLR10 | Viral and bacterial dsRNA and other products | (172) |
| NOD1* | Mainly gram-negative bacteria amino acids | (173) |
| NOD2 | Muramyl dipeptides of bacterial peptidoglycans | (173) |
* Indicates expression by SC (160).