Figure 5.

Ex vivo optical imaging and confocal microscopy with L-PEG₂₀₀₀-DBCO and L-PEG₂₀₀₀ in tumor tissues and liver of MDA-MB-231 tumor xenograft: (a) control experiment of demonstrating equal fluorescence intensity of L-PEG₂₀₀₀ and L-PEG₂₀₀₀-DBCO, (b) ex vivo optical imaging with L-PEG₂₀₀₀-DBCO and L-PEG₂₀₀₀ in tumor tissues and the liver, (c) quantitative uptake based on fluorescent signal intensity of L-PEG₂₀₀₀-DBCO and L-PEG₂₀₀₀ in tumor tissues and the liver at 24 h post liposome administration and (d) confocal microscopy imaging of L-PEG₂₀₀₀-DBCO and L-PEG₂₀₀₀ in tumor tissue and liver sections.