Table 3.
Primary and secondary outcomes comparing patients in treatment vs. control groups (n = 135).
| Variables | Treatment group (n = 27) | Control group (n = 108) | p-value |
|---|---|---|---|
| Number (%) or Median (IQR) | |||
| Primary outcomes | |||
| PICU LOS (days) | 3.63 (1.70–7.80) | 1.09 (0.66–1.95) | <0.01a |
| MVb | 7 (25.9) | 20 (18.5) | 0.39c |
| Secondary outcomes | |||
| Duration of MV (days) | 4.96 (2–13) | 1.60 (0.69–4.75) | 0.02a |
| Non-invasive ventilation | |||
| Received non-invasive ventilationd | 27 (100) | 98 (90.7) | 0.21e |
| Duration of non-invasive ventilation (days) | 2.92 (2.04–8.29) | 1.44 (0.88–2.67) | <0.01a |
| ECMO | |||
| Received ECMO | 3 (11.1) | 0 (0) | <0.01e |
| Duration on ECMO (days) | 2.6 (0.4–12.4) | – | – |
| Mortality | 1 (3.7) | 4 (3.7) | 1.00e |
IQR, Interquartile range; PICU LOS, Pediatric intensive care unit length of stay; MV, Mechanical ventilation; ECMO, Extracorporeal membrane oxygenation.
a
Wilcoxon two-sample test.
b
In the treatment group, four out of seven patients were mechanically ventilated before starting magnesium continuous infusion.
c
Chi-square test.
d
Non-invasive ventilation included high flow nasal canula, continuous positive airway pressure, and/or bilevel positive airway pressure.
e
Fisher's Exact test.
fExact Chi-square test.