Table 5.
Logistic and linear regression models looking at mechanical ventilation requirement and PICU LOS.
| Variables | Reference value | GEE logistic regression for mechanical ventilation (n = 115*) | Variables | Reference value | GEE linear regression for PICU length of stay (days) (n = 135) | ||
|---|---|---|---|---|---|---|---|
| Odds ratio (95% confidence interval) | p-value | Model parameter estimate (95% confidence interval) | p-value | ||||
| Intercept | 0.013 (0.003–0.063) | <0.01 | Intercept | −0.091 (−0.593 to 0.411) | 0.72 | ||
| Received magnesium infusion (n = 23) | No magnesium infusions (n = 92) | 0.031 (0.001–1.201) | 0.06 | Received magnesium infusions (n = 27) | No magnesium infusions (n = 108) | −0.148 (−1.09 to 0.793) | 0.76 |
| Received ketamine infusions (n = 18) | No ketamine infusions (n = 97) | 19.294 (5.404–68.882) | <0.01 | Received ketamine infusions (n = 27) | No ketamine infusions (n = 108) | 0.852 (−0.219 to 1.92) | 0.12 |
| Total prednisone equivalent dose (mg/kg) | Mean = 12.24, any 1-unit increase | 1.099 (1.029–1.173) | <0.01 | Total prednisone equivalent dose (mg/kg) | Mean = 14.11, any 1-unit increase | 0.128 (0.096–0.160) | <0.01 |
| Continuous albuterol duration (days) | Mean = 1.43, any 1-unit increase | 1.053 (0.696–1.592) | 0.81 | Continuous albuterol duration (days) | Mean = 1.54, any 1-unit increase | 0.297 (−0.014 to 0.609) | 0.06 |
Patients who received magnesium were optimally matched 1:4 to those who did not receive magnesium using propensity scores generated on sex, obesity, age at admission, PIM III and PRISM III scores. Propensity scores were used in both models to account for matching process.
*
Four patients received magnesium after mechanical ventilation and were excluded from the logistic regression model along with their matched controls.