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. 2022 Jun 9;12:804287. doi: 10.3389/fonc.2022.804287

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Copyright © 2022 Chen, Hong, Zhou and Qin

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Correlation between CDH2, FRMD3 and immune cell infiltration in THCA. (A, B) The correlation of stromal scores, immune scores and ESTIMATE scores and CDH2 (A), FRMD3 (B) expression and of TCGA dataset in THCA. (C) The relationship between CDH2 expression and immune cells was calculated by ssGSEA method in TCGA dataset. (D) The correlation between different CDH2 levels and T cell enrichment in TCGA dataset. (E) The correlation between CDH2 expression and T cell enrichment by spearman correlation analysis. (F) The relationship between FRMD3 expression and immune cells was calculated by ssGSEA method in TCGA dataset. (G) The correlation between different FRMD3 levels and T cell enrichment in TCGA dataset. (H) The correlation between FRMD3 expression and T cell enrichment by spearman correlation analysis. *P < 0.05; ***P < 0.001.