Table 2.
Results of PET neuroimaging analyses.
| Modality [contrast] | Region | MNI coordinates | Statistics | Cluster size | |
|---|---|---|---|---|---|
| x/y/z | t-value | p-value (FWE) | |||
| FDG-PET | |||||
| [BL < HC] | Left midbrain | −12/−20/−20 | 4.525 | 0.028 | 35 |
| [FU < HC] | Bilateral midbrain | −6/−20/−18 | 5.55 | <0.001 | 227 |
| [FU < BL] | Left midbrain | −8/−10/−16 | 4.70 | 0.045 | 22 |
| FDOPA PET | |||||
| [BL < HC] | Left putamen | −28/−8/−6 | 5.40 | 0.012 | 187 |
| Right putamen | 28/−8/2 | 5.37 | 0.017 | 155 | |
| [FU < HC] | Left putamen | −28/−14/−2 | 7.69 | 0.003 | 362 |
| Right putamen | 28/−10/2 | 8.59 | 0.009 | 228 | |
| Right caudate | 16/6/14 | 4.33 | 0.033 | 99 | |
| [FU < BL] | Right caudate | 8/12/−2 | 9.73 | 0.001 | 220 |
Statistical details of PET analyses by contrast and modality. All t-values were calculated using SPM12. For FDG-PET, p-values after small-volume-correction for midbrain and for FDOPA PET after small-volume-correction for striatum are shown, respectively.