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. 2022 Jun 17;50:101494. doi: 10.1016/j.eclinm.2022.101494

Table 1.

Demographic and clinical characteristics of TBI patients.

TBI(n=51) 12-month Outcome
p-valuea
Unfavorable (GOS-E 1-4) (n=11) Favorable (GOS-E 5-8) (n=40)
Age, years mean (SD) 56·51 (16·40) 59·63 (11·48) 55·65 (17·53) 0·48
(range) (20-89)
Sex, n (%)
 Female 12 (23·53) 1 (9·09) 11 (27·50) 0·42
 Male 39 (76·47) 10 (90·91) 29 (72·50)
Race, n (%)
 Caucasian 51 (100) 11 (100) 40 (100)
GCS
 Median (IQR) 12 (3-12) 3 (3-8) 12 (12-12) 0·0001
Trauma history, n (%)
 Motor Vehicle Accident 3 (5·88) 0 (0) 3 (7·50)
 Motor Bicycle Accident 8 (15·68) 3 (27·27) 5 (12·50) 0·77
 Fall 37 (72·55) 8 (72·73) 29 (72·50)
 Gun Shoot 1 (1·96) 0 (0) 1 (2·50)
 Assault 1 (1·96) 0 (0) 1 (2·50)
 Other 1 (1·96) 0 (0) 1 (2·50)
Time to first sample withdrawal, h,
Median (IQR)
13.5 (7.7-17.7) 14.1 (9.3-22.7) 14.1 (8.2-18.7) 0.66
Extracranial injures, n (%) 12 (23·53) 5 (45·45) 7 (17·50) 0·05
Image Findings, n (%)
 Contusion 11 (22) 1 (9·09) 10 (25)
 DAI 2 (4) 0 (0) 2 (5) 0·6
 Extra-axial lesions 20 (39) 4 (36·36) 16 (40)
 Mixed Lesions 18 (35) 6 (54·55) 12 (30)
Marshall Score, n (%)
Diffuse Injury
 1 2 (3·92) 0 (0) 2 (5)
 2 34 (66·67) 4 (36·36) 30 (75) 0·02
Mass lesions
 5 14 (27·45) 7 (63·64) 7 (17·50)
 6 1 (1·96) 0 (0) 1 (2·50)
Edema, n (%)
 Yes 6 (11·76) 2 (18·18) 4 (10)
 No 45 (88·24) 9 (81·82) 36 (90) 0·6
Decompressive Craniectomy, n (%)
 Yes 10 (19·61) 6 (54·55) 4 (10)
 No 41 (80·39) 5 (45·45) 36 (90) 0·004
GOS-E 12 months, n (%)
Poor outcome
 1 10 (19·61) 10 (90·90) -
 3 1 (1·96) 1 (9·1) -
Good outcome
 6 2 (3·92) - 2 (5)
 7 2 (3·92) - 2 (5)
 8 36 (70·59) - 36 (90)
a

p values of the t-Test or Mann-Whitney U test, as appropriate, for continuous variables, Fisher's exact test for categorical variables, for differences between the 2 groups [unfavorable versus favorable outcome]).

DAI, Diffuse axonal Injury; GCS, Glasgow Coma Scale; GOS-E, Glasgow Outcome Scale-Extended; IQR, interquartile range.