Table 2.

Model parameters

Parameter	Value	Lower bound	Upper bound
k1	Calibrated	5 × 10−4/(nM s)	5 × 10−2/(nM s)
KD1	504
k1′	k1 × KD1
k2	k2′/KD2
KD2	Calculated according to PS, l, and m (Equation 13).
k2′	Calibrated	2.5 × 10−6/s	2.5 × 10−4/s
k3	Calibrated0 Calibrated and calculated according to PS and x (Equation 22)1	7 × 10−7/(nM2 s)	7 × 10−5/(nM2 s)
KD3	2004
k3′	k3 × KD3
k4	Calibrated0 Calibrated and calculated according to PS and x (Equation 22)2	1.5 × 10−4/(nM s)	1.5 × 10−2/(nM s)
k4,1′	Calibrated	7 × 10−2/s	7/s
k4,i′	Calculated according to PS, i, y, t1–3, and u1–3 (Equation 20)
k5	Calibrated0 Calibrated and calculated according to PS and x (Equation 22)3	7 × 10−6/s	7 × 10−4/s
r1	Calibrated	0.2 nM/s	20 nM/s
r2	d2 × C(0) (nM).
d1	2.25 × 10−5 (78)
d2	2.59 × 10−5 (79)
n	770 (80, 81)
x	Calibrated1,2,3	0	3.33
y	Calibrated	3	7
g	35.2, fitted
h	1.48 × 104, fitted
l	9.20 × 10−6, fitted
m	4.52 × 10−4, fitted
t1–3	Fitted and calculated according to y
u1–3	Fitted and calculated according to y

0: ‘Stabilization’ model.

1, 2, 3: “Hexamer,” “Filament,” and “Budding” models.

4: Data from Dr Stahelin (available on request).