Table 5.
Inhibitory activities of ligand and its metal complex against α-amylase and α-glucosidase enzymes.
| Test Compounds | IC50x,y (mg/mL) |
|
|---|---|---|
| Enzymes | ||
| α-amylase | α-glucosidase | |
| HL | 3.08 ± 0.16 | 2.14 ± 1.78 |
| HL-Cu | 1.55 ± 3.33 | 1.08 ± 0.34 |
| HL-Zn | 1.65 ± 0.47 | 1.11 ± 0.33 |
| Standardˆ | 0.50 ± 0.21 | 0.70 ± 0.24 |
x
Values are expressed as mean ± SE. Means in the same row with distinct superscripts are significantly different (p ≤ 0.05) as separated by Duncan multiple range test.
y
The IC50 value is defined as the inhibitor concentration to inhibit 50% of enzyme activity under assay conditions.
ˆ
Standard: Acarbose (positive control).