Table 2.
Young's modulus and hardness (mean ± standard deviation) at 3 weeks post-injection of breast cancer cells, obtained from nanoindentation mechanical tests in each region and bone tissue type of each femur. Includes mean ± standard deviation (CTRL n = 7, MET-IPS n = 5, MET-CONTRA n = 5). ††p < 0.01, relative to MET-IPS.
| Proximal Femur |
Distal Femur |
|||||
|---|---|---|---|---|---|---|
| CTRL | MET-IPS | MET-CONTRA | CTRL | MET-IPS | MET-CONTRA | |
| Cortical bone | ||||||
| Young's modulus (GPa) | 17.23 ± 2.71 | 15.92 ± 0.32 | 15.66 ± 3.29 | 17.95 ± 1.39 | 16.96 ± 0.76 | 18.18 ± 0.95 |
| Hardness (GPa) | 0.58 ± 0.10 | 0.54 ± 0.03 | 0.57 ± 0.18 | 0.60 ± 0.04 | 0.55 ± 0.03 | 0.65 ± 0.14 |
| Trabecular bone | ||||||
| Young's modulus (GPa) | 14.88 ± 1.80 | 16.20 ± 1.32 | 14.99 ± 2.56 | 15.94 ± 1.75 | 16.88 ± 0.55 | 14.67 ± 0.76†† |
| Hardness (GPa) | 0.52 ± 0.05 | 0.57 ± 0.06 | 0.66 ± 0.14 | 0.52 ± 0.06 | 0.60 ± 0.05 | 0.60 ± 0.04 |