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. 2022 Jun 9;9:858720. doi: 10.3389/fcvm.2022.858720

TABLE 3.

Clinical features of 3 patients with acute MI and developed both cardiac rupture (CR) and left ventricular thrombus (LVT).

Variable Case 1 Case 2 Case 3
Sex Male Female Male
Age (year) 67 78 70
Diagnosis method Echocardiography Echocardiography Echocardiography + Pericardiocentesis
Revascularization PCI CAG PCI
Type of MI STEMI STEMI STEMI
Location of MI anterior anterior + inferior anterior
Rupture type ventricular septum ventricular septum Free wall
LVT localization Apex anterior/septum apex
MI-to-CR interval (day) 1 5 5
MI-to-LVT interval (day) 14 26 3
Ventricular aneurysm (VA) Yes Yes Yes
Timing of VA and LVT LVT prior to VA simultaneously simultaneously
Pericardial effusion Yes Yes No
Killip class IV III I
Percutaneous closure No Yes No
Surgical repair No No No
Days of hospitalization 6 37 5
Outcome Survived Deceased deceased
WBC count (109/L) 7.07 14.73 7.15
Lymphocyte count (109/L) 1.6 1.94 1.41
Monocyte count (109/L) 0.54 0.85 0.59
Neutrophil count (109/L) 4.77 11.9 4.94
Platelet count (109/L) 265 227 178
Mean platelet volume (fl) 9.3 11.7 11.1
Fibrinogen (mg/L) 2.93 5.35 4.71
FDP (mg/L) 5.7 16.85 2.48
D dimer (mg/L) 2.6 5.61 1.53
hsCRP (mg/L) >9.5 >9.5 n.d.
AST (U/L) 24 282 38
LDH (U/L) 305 1039 413
HBDH (U/L) 290 396 398
Creatine kinase (U/L) 137 135 193
CK-MB (U/L) 11 17 17
hs-TnT (U/L) 0.46 3.7 2.97

PCI, percutaneous coronary intervention; CAG, coronary artery angiogram only; STEMI, ST-elevation myocardial infarction; hsCRP, highly sensitive C-reactive protein; FDP, fibrinogen degradation products; AST, aspartate transaminase; LDH, lactate dehydrogenase; HBDH, α- hydroxybutyrate dehydrogenase; CK-MB, creatine kinase-myocardial band; hs-TnT, highly sensitive-troponin-T; n.d., not done.