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. 2022 Jun 9;12:786981. doi: 10.3389/fonc.2022.786981

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Copyright © 2022 Wang, Wei, Hu, Pan, Wu, Wang, Zhang, Shi, Liu, Zhao, Zhu and Ye

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Kaplan–Meier curves of patients with different FAI_PTAT. Fat attenuation index (FAI) was calculated and grouped according to the median FAT value of the FUSCC and TCGA cohorts. (A) Overall survival of the TCGA cohort, the 5-year median overall survival was 64 months for high FAI_PTAT group and not reached for low FAI_PTAT group (HR = 2.24, p <0.001). (B) Overall survival of the FUSCC cohort, the 5-year median overall survival was not reached for both groups in FUSCC cohort (HR = 2.28, p = 0.01). The 3-year survival rate was 88%/93% for high FAI_PTAT and low FAI_PTAT groups in FUSCC cohort (HR = 1.81) and 72%/93% in TCGA cohort (HR = 5.65).