Table 2.
Univariate and Multivariate analysis for overall survival in patients with ccRCC.
| Characteristics | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p-value | HR | 95% CI | p-value | |
| TCGA cohort | ||||||
| Gender | 1.46 | 0.88–2.42 | 0.14 | 0.93 | 0.52–1.69 | 0.82 |
| Age | 1.04 | 1.02–1.06 | 0.000 | 1.04 | 1.018–1.068 | 0.001 |
| BMI | 0.49 | 0.35–0.70 | 0.000 | 0.55 | 0.38–0.79 | 0.001 |
| T stage | 1.97 | 1.5–2.57 | 0.000 | 1.31 | 0.92–1.88 | 0.13 |
| N stage | 4.00 | 1.25–12.84 | 0.02 | 0.40 | 0.09–1.84 | 0.24 |
| M stage | 4.53 | 2.71–7.56 | 0.000 | 2.44 | 1.35–4.43 | 0.003 |
| Pathological Grade | 1.63 | 0.93–2.84 | 0.09 | 0.61 | 0.32–1.19 | 0.15 |
| △FAIPTAT | 2.33 | 1.36–4.01 | 0.002 | 1.28 | 0.61–2.72 | 0.51 |
| FAIPTAT | 2.81 | 1.59–4.96 | 0.000 | 2.14 | 1.15–3.99 | 0.017 |
| FUSCC cohort | ||||||
| Gender | 1.57 | 0.66–3.73 | 0.31 | 2.49 | 0.97–6.16 | 0.056 |
| Age, years | 1.003 | 0.96–1.04 | 0.86 | 0.99 | 0.95–1.05 | 0.96 |
| BMI | 1.03 | 0.44–1.97 | 0.85 | 1.06 | 0.44–2.52 | 0.89 |
| T stage | 1.93 | 0.64–5.75 | 0.23 | 1.03 | 0.27–3.98 | 0.96 |
| N stage | 3.62 | 0.48–27.2 | 0.21 | 1.73 | 0.22–13.60 | 0.60 |
| M stage | 15.21 | 3.37–68.6 | 0.000 | 9.26 | 1.88–45.5 | 0.006 |
| Pathological Grade | 4.00 | 1.35–11.92 | 0.013 | 3.53 | 1.16–10.68 | 0.026 |
| △FAIPTAT | 2.42 | 0.94–6.23 | 0.068 | 1.18 | 0.34–4.11 | 0.79 |
| FAIPTAT | 3.31 | 1.21–9.05 | 0.019 | 3.14 | 1.11–8.88 | 0.031 |
HR, Hazard Ratio; CI, Confidence Interval; FAI, Fat Attenuation Index; BMI, Body Mass Index.