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. 2022 Jun 9;9:852022. doi: 10.3389/fmed.2022.852022

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Copyright © 2022 Huang, Chang, Meng, Lin, Lai, Hsia, Chen, Tien, Bair, Lin, Chen and Tsai.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Final CRT significantly improved after treatment. (B) Mean CRT improved significantly after the third month and continuously improved up to the end of the study (month 12) (*p < 0.05 compared to before-treatment data).