TABLE 6.
Causes of death within 5 years after HTX – stratified by T2DM at HTX.
| Parameter | All (n = 376) | T2DM (n = 121) | No T2DM (n = 255) | Difference | 95% CI | P-value |
| Graft failure, n (%) | 38 (10.1%) | 18 (14.9%) | 20 (7.8%) | 7.1% | 0.1 – 14.1% | 0.035* |
| Acute rejection, n (%) | 4 (1.1%) | 1 (0.8%) | 3 (1.2%) | 0.4% | –1.7 – 2.5% | 0.757 |
| Infection/Sepsis, n (%) | 66 (17.5%) | 20 (16.5%) | 46 (18.0%) | 1.5% | –6.6 – 9.6% | 0.719 |
| Malignancy, n (%) | 8 (2.1%) | 5 (4.1%) | 3 (1.2%) | 2.9% | –0.9 – 6.7% | 0.064 |
| Thromboembolic event/bleeding, n (%) | 10 (2.7%) | 6 (5.0%) | 4 (1.6%) | 3.4% | –0.8 – 7.6% | 0.056 |
| All causes, n (%) | 126 (33.5%) | 50 (41.3%) | 76 (29.8%) | 11.5% | 1.1 – 21.9% | 0.027* |
CI, confidence interval; HTX, heart transplantation; n, number; T2DM, type 2 diabetes mellitus; *, statistically significant (P < 0.050).