FIGURE 4.

Changes in afterload, stroke volume and right ventricular (RV) mass after the start of treatment. Patients with high baseline end-diastolic elastance (E_ed) either improved to <0.63 mmHg·mL⁻¹ (green; E_ed responders) or remained high at >0.63 mmHg·mL⁻¹ (red; non-responders). Dots and whiskers represent mean±sem. p-values were determined through pairwise t-test with Bonferroni correction. p-interaction values represent repeated measures ANOVA. a) Arterial elastance (E_a) improved in the E_ed responders. b) RV stroke volume index improved significantly in E_ed responders, while there was no change in non-responders. c) The change in RV mass index was stronger in E_ed responders. BL: baseline; FU: follow-up; ns: nonsignificant.