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. 2022 Jun 9;13:868572. doi: 10.3389/fendo.2022.868572

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Copyright © 2022 Feng, Divall, Jones, Ubba, Fu, Yang, Wang, Yang and Wu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Androgen receptor (Ar) is specifically deleted in liver. (A) Ar mRNA levels of LivARKO compared to control littermates, measured by qRT-PCR, in liver, ovary, uterus, hypothalamus, pituitary, gonadal fat, and skeletal muscles. (B) PCR analysis of Ar liver genomic DNA from control and LivARKO mouse. Arrows pointed to a 952 bp Ar floxed band in liver of control mouse and a knockout band 404 bp in liver of LivARKO mouse. Two-tailed student’s t-tests were applied. P-values were stated in the graphs. N=4-5. Values were mean ± S.E.M.