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. 2022 Jun 9;13:868809. doi: 10.3389/fimmu.2022.868809

Table 4.

Univariate and multivariate logistic regression analyses of baseline variables predicting PD in training set (n = 93).

Factors Univariate Multivariate
OR 95% CI P Value OR 95% CI P Value
Age 0.981 0.945-1.018 0.308
Gender: Male/Female 1.439 0.434-4.773 0.552
AFP (ng/mL): 0.514
<20*
20-400 2.000 0.569-7.028 0.280
>400 1.538 0.560-4.230 0.404
ALT (U/L) 0.998 0.992-1.005 0.629
AST (U/L) 0.999 0.993-1.005 0.773
PT (s) 1.053 0.814-1.362 0.694
ALB (g/L) 1.009 0.932-1.093 0.829
PLT (109/L) 1.001 0.997-1.006 0.592
TBIL (µmol/L) 1.002 0.957-1.050 0.923
BCLC stage: B/C 0.769 0.271-2.184 0.622
ECOG performance: 0.909
0*
1 1.229 0.452-3.342 0.687
2 1.306 0.111-15.299 0.832
Child-Pugh: B/A 1.101 0.308-3.936 0.882
ALBI grade:1/2 0.124 0.044-0.354 <0.001 0.107 0.032-0.359 <0.001
Tumor number: ≥3/<3 1.857 0.746-4.623 0.183
Tumor size (cm) 0.938 0.841-1.046 0.252
Embolus: Present/Absent 1.568 0.615-3.998 0.347
Extrahepatic metastasis: Present/Absent 1.061 0.360-3.132 0.914
LS value of tumor by SWE (kPa) 1.139 1.063-1.222 <0.001 1.148 1.064-1.239 <0.001
LS value of adjacent normal liver tissue by SWE (kPa) 0.999 0.946-1.055 0.962

AFP, α-fetoprotein; ALB, albumin; ALBI, albumin-bilirubin; ALT, alanine aminotransferase; AST, aspartate aminotransferase; ECOG, Eastern Cooperative Oncology Group; LS, liver stiffness; PD, Progressive disease; PLT, platelet count; PT, prothrombin time; TBIL, total bilirubin; SWE, shear-wave elastography.

*Used as the reference category.

Bold values are values with statistical differences (P value<0.05).