Table 5.
Performance of baseline LS value in predicting PD in training set (n = 93).
| Cut-off values | Sensitivity (%) | 95% CI | Specificity (%) | 95% CI | +LR | -LR |
|---|---|---|---|---|---|---|
| >=3.97 | 100 | 87.2 - 100.0 | 0 | 0.0 - 5.4 | 1 | |
| >3.97 | 100 | 87.2 - 100.0 | 1.52 | 0.04 - 8.2 | 1.02 | 0 |
| >5.07 | 100 | 87.2 - 100.0 | 3.03 | 0.4 - 10.5 | 1.03 | 0 |
| >5.15 | 100 | 87.2 - 100.0 | 4.55 | 0.9 - 12.7 | 1.05 | 0 |
| >5.39 | 100 | 87.2 - 100.0 | 6.06 | 1.7 - 14.8 | 1.06 | 0 |
| >7.21 | 100 | 87.2 - 100.0 | 7.58 | 2.5 - 16.8 | 1.08 | 0 |
| >7.66 | 96.3 | 81.0 - 99.9 | 7.58 | 2.5 - 16.8 | 1.04 | 0.49 |
| >8.17 | 96.3 | 81.0 - 99.9 | 9.09 | 3.4 - 18.7 | 1.06 | 0.41 |
| >8.27 | 96.3 | 81.0 - 99.9 | 10.61 | 4.4 - 20.6 | 1.08 | 0.35 |
| >9.08 | 96.3 | 81.0 - 99.9 | 12.12 | 5.4 - 22.5 | 1.1 | 0.31 |
| >9.19 | 96.3 | 81.0 - 99.9 | 13.64 | 6.4 - 24.3 | 1.12 | 0.27 |
| >9.51 | 96.3 | 81.0 - 99.9 | 15.15 | 7.5 - 26.1 | 1.13 | 0.24 |
| >9.61 | 96.3 | 81.0 - 99.9 | 16.67 | 8.6 - 27.9 | 1.16 | 0.22 |
| >9.72 | 96.3 | 81.0 - 99.9 | 18.18 | 9.8 - 29.6 | 1.18 | 0.2 |
| >10.16 | 96.3 | 81.0 - 99.9 | 19.7 | 10.9 - 31.3 | 1.2 | 0.19 |
| >10.83 | 92.59 | 75.7 - 99.1 | 19.7 | 10.9 - 31.3 | 1.15 | 0.38 |
| >10.94 | 92.59 | 75.7 - 99.1 | 24.24 | 14.5 - 36.4 | 1.22 | 0.31 |
| >11.11 | 92.59 | 75.7 - 99.1 | 25.76 | 15.8 - 38.0 | 1.25 | 0.29 |
| >11.17 | 92.59 | 75.7 - 99.1 | 27.27 | 17.0 - 39.6 | 1.27 | 0.27 |
| >11.29 | 92.59 | 75.7 - 99.1 | 28.79 | 18.3 - 41.3 | 1.3 | 0.26 |
| >11.52 | 92.59 | 75.7 - 99.1 | 30.3 | 19.6 - 42.9 | 1.33 | 0.24 |
| >11.88 | 88.89 | 70.8 - 97.6 | 31.82 | 20.9 - 44.4 | 1.3 | 0.35 |
| >12.2 | 85.19 | 66.3 - 95.8 | 31.82 | 20.9 - 44.4 | 1.25 | 0.47 |
| >12.54 | 85.19 | 66.3 - 95.8 | 33.33 | 22.2 - 46.0 | 1.28 | 0.44 |
| >12.6 | 85.19 | 66.3 - 95.8 | 34.85 | 23.5 - 47.6 | 1.31 | 0.43 |
| >12.76 | 85.19 | 66.3 - 95.8 | 36.36 | 24.9 - 49.1 | 1.34 | 0.41 |
| >13.02 | 85.19 | 66.3 - 95.8 | 37.88 | 26.2 - 50.7 | 1.37 | 0.39 |
| >13.1 | 85.19 | 66.3 - 95.8 | 39.39 | 27.6 - 52.2 | 1.41 | 0.38 |
| >13.23 | 85.19 | 66.3 - 95.8 | 40.91 | 29.0 - 53.7 | 1.44 | 0.36 |
| >13.29 | 85.19 | 66.3 - 95.8 | 42.42 | 30.3 - 55.2 | 1.48 | 0.35 |
| >13.36 | 85.19 | 66.3 - 95.8 | 43.94 | 31.7 - 56.7 | 1.52 | 0.34 |
| >13.74 | 85.19 | 66.3 - 95.8 | 45.45 | 33.1 - 58.2 | 1.56 | 0.33 |
| >14.39 | 85.19 | 66.3 - 95.8 | 46.97 | 34.6 - 59.7 | 1.61 | 0.32 |
| >14.92 | 85.19 | 66.3 - 95.8 | 48.48 | 36.0 - 61.1 | 1.65 | 0.31 |
| >15.05 | 85.19 | 66.3 - 95.8 | 50 | 37.4 - 62.6 | 1.7 | 0.3 |
| >15.23 | 85.19 | 66.3 - 95.8 | 51.52 | 38.9 - 64.0 | 1.76 | 0.29 |
| >15.32 | 85.19 | 66.3 - 95.8 | 53.03 | 40.3 - 65.4 | 1.81 | 0.28 |
| >15.34 | 85.19 | 66.3 - 95.8 | 54.55 | 41.8 - 66.9 | 1.87 | 0.27 |
| >15.35 | 85.19 | 66.3 - 95.8 | 56.06 | 43.3 - 68.3 | 1.94 | 0.26 |
| >15.46 | 85.19 | 66.3 - 95.8 | 57.58 | 44.8 - 69.7 | 2.01 | 0.26 |
| >15.5 | 81.48 | 61.9 - 93.7 | 57.58 | 44.8 - 69.7 | 1.92 | 0.32 |
| >15.87 | 81.48 | 61.9 - 93.7 | 59.09 | 46.3 - 71.0 | 1.99 | 0.31 |
| >16.22 | 81.48 | 61.9 - 93.7 | 60.61 | 47.8 - 72.4 | 2.07 | 0.31 |
| >16.29 | 81.48 | 61.9 - 93.7 | 62.12 | 49.3 - 73.8 | 2.15 | 0.3 |
| >16.64 | 81.48 | 61.9 - 93.7 | 63.64 | 50.9 - 75.1 | 2.24 | 0.29 |
| >16.85 | 81.48 | 61.9 - 93.7 | 66.67 | 54.0 - 77.8 | 2.44 | 0.28 |
| >17.13 | 81.48 | 61.9 - 93.7 | 68.18 | 55.6 - 79.1 | 2.56 | 0.27 |
| >17.14 | 74.07 | 53.7 - 88.9 | 68.18 | 55.6 - 79.1 | 2.33 | 0.38 |
| >18.09 | 74.07 | 53.7 - 88.9 | 69.7 | 57.1 - 80.4 | 2.44 | 0.37 |
| >18.57 | 74.07 | 53.7 - 88.9 | 71.21 | 58.7 - 81.7 | 2.57 | 0.36 |
| >18.6 | 70.37 | 49.8 - 86.2 | 71.21 | 58.7 - 81.7 | 2.44 | 0.42 |
| >19.02 | 70.37 | 49.8 - 86.2 | 72.73 | 60.4 - 83.0 | 2.58 | 0.41 |
| >19.2 | 70.37 | 49.8 - 86.2 | 75.76 | 63.6 - 85.5 | 2.9 | 0.39 |
| >19.35 | 70.37 | 49.8 - 86.2 | 77.27 | 65.3 - 86.7 | 3.1 | 0.38 |
| >19.51 | 70.37 | 49.8 - 86.2 | 78.79 | 67.0 - 87.9 | 3.32 | 0.38 |
| >19.53 * | 70.37 | 49.8 - 86.2 | 80.3 | 68.7 - 89.1 | 3.57 | 0.37 |
| >19.81 | 66.67 | 46.0 - 83.5 | 80.3 | 68.7 - 89.1 | 3.38 | 0.42 |
| >19.88 | 62.96 | 42.4 - 80.6 | 80.3 | 68.7 - 89.1 | 3.2 | 0.46 |
| >19.94 | 59.26 | 38.8 - 77.6 | 80.3 | 68.7 - 89.1 | 3.01 | 0.51 |
| >20.44 | 51.85 | 31.9 - 71.3 | 80.3 | 68.7 - 89.1 | 2.63 | 0.6 |
| >20.75 | 51.85 | 31.9 - 71.3 | 84.85 | 73.9 - 92.5 | 3.42 | 0.57 |
| >21.07 | 51.85 | 31.9 - 71.3 | 87.88 | 77.5 - 94.6 | 4.28 | 0.55 |
| >22.03 | 48.15 | 28.7 - 68.1 | 87.88 | 77.5 - 94.6 | 3.97 | 0.59 |
| >22.87 | 44.44 | 25.5 - 64.7 | 87.88 | 77.5 - 94.6 | 3.67 | 0.63 |
| >23.02 | 40.74 | 22.4 - 61.2 | 89.39 | 79.4 - 95.6 | 3.84 | 0.66 |
| >23.09 | 40.74 | 22.4 - 61.2 | 90.91 | 81.3 - 96.6 | 4.48 | 0.65 |
| >23.52 | 37.04 | 19.4 - 57.6 | 90.91 | 81.3 - 96.6 | 4.07 | 0.69 |
| >23.86 | 33.33 | 16.5 - 54.0 | 90.91 | 81.3 - 96.6 | 3.67 | 0.73 |
| >25.4 | 33.33 | 16.5 - 54.0 | 92.42 | 83.2 - 97.5 | 4.4 | 0.72 |
| >26.46 | 29.63 | 13.8 - 50.2 | 92.42 | 83.2 - 97.5 | 3.91 | 0.76 |
| >26.64 | 29.63 | 13.8 - 50.2 | 93.94 | 85.2 - 98.3 | 4.89 | 0.75 |
| >26.96 | 25.93 | 11.1 - 46.3 | 93.94 | 85.2 - 98.3 | 4.28 | 0.79 |
| >28.27 | 22.22 | 8.6 - 42.3 | 93.94 | 85.2 - 98.3 | 3.67 | 0.83 |
| >29.14 | 22.22 | 8.6 - 42.3 | 95.45 | 87.3 - 99.1 | 4.89 | 0.81 |
| >29.31 | 22.22 | 8.6 - 42.3 | 96.97 | 89.5 - 99.6 | 7.33 | 0.8 |
| >30.91 | 18.52 | 6.3 - 38.1 | 96.97 | 89.5 - 99.6 | 6.11 | 0.84 |
| >32.08 | 14.81 | 4.2 - 33.7 | 96.97 | 89.5 - 99.6 | 4.89 | 0.88 |
| >33.07 | 14.81 | 4.2 - 33.7 | 98.48 | 91.8 - 100.0 | 9.78 | 0.86 |
| >34.07 | 11.11 | 2.4 - 29.2 | 98.48 | 91.8 - 100.0 | 7.33 | 0.9 |
| >35.29 | 7.41 | 0.9 - 24.3 | 98.48 | 91.8 - 100.0 | 4.89 | 0.94 |
| >36.54 | 3.7 | 0.09 - 19.0 | 98.48 | 91.8 - 100.0 | 2.44 | 0.98 |
| >38.02 | 3.7 | 0.09 - 19.0 | 100 | 94.6 - 100.0 | 0.96 | |
| >39.43 | 0 | 0.0 - 12.8 | 100 | 94.6 - 100.0 | 1 |
LS, Liver stiffness; PD, Progressive disease; CI, confidence Interval; +LR, positive likelihood ratio; -LR, negative likelihood ratio; *: the cut-off value has the highest sum of sensitivity and specificity.
Bold values are values with statistical differences (P value<0.05).