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. 2022 Jun 9;9:905718. doi: 10.3389/fcvm.2022.905718

TABLE 3.

Subgroup analysis of hemodynamic and morphologic comparisons between (1) patients with and without adverse outcomes (2) rapid v. slow aortic growth.

De novo TBAD

Indexed parameter (per mm) No adverse outcome (n = 17) Adverse outcome (n = 9) P-value P-value (MV) Rapid aortic growth (n = 5) Slow aortic growth (n = 13) P-value P-value (MV)
FL mean stasis (%) 1.59 ± 0.51 1.16 ± 0.40 0.03* 0.15 1.28 ± 0.22 1.51 ± 0.58 0.24
FL mean reverse flow (mL/cycle) 2.82E-4 ± 1.09E-4 2.39E-4 ± 1.01E-4 0.31 1.80E-4 ± 4.99E-5 2.55E-4 ± 8.41E-5 0.04* 0.99
TL peak velocity (cm/s) 5.78 ± 2.52 3.68 ± 1.33 0.03* 0.13 3.45 ± 9.78E-1 5.59 ± 2.72 0.21
KER 2.53E-3 ± 1.57E-3 3.95E-3 ± 3.23E-3 0.39 4.85E-3 ± 1.56E-3 2.11E-3 ± 1.07E-3 0.01* 0.99
Baseline diameter (mm) 41.59 ± 9.02 50.67 ± 7.94 0.02* 46.20 ± 7.60 44.23 ± 10.49 0.67
FL diameter (mm) 37.41 ± 10.40 46.56 ± 7.84 0.03* 41.40 ± 3.78 40.15 ± 9.37 0.48

Repaired TAAD with Residual TBAD

Indexed parameter (per mm) No adverse outcome (n = 22) Adverse outcome (n = 3) Rapid aortic growth (n = 5) Slow aortic growth (n = 19) P-value P-value (MV)

FL mean reverse flow (mL/cycle) 3.38E-4 ± 1.67E-4 1.77E-4 [1.15E-4, 2.10 E-4] 2.93E-4 ± 1.77E-4 3.28E-4 ± 1.72E-4 0.68
TL mean FF (mL/cycle) 2.79E-3 ± 8.78E-4 1.90E-3 [1.38E-3, 1.94E-3] 2.69E-3 ± 9.81E-4 2.65E-3 ± 9.24E-4 0.68
Baseline diameter (mm) 41.77 ± 5.83 51 [47, 52] 45.60 ± 5.13 42.58 ± 5.98 0.30
Entry Tear diameter (mm) 5.73 ± 4.93 9 [9, 10] 5.60 ± 3.65 6.84 ± 5.00 0.55
FL diameter (mm) 39.05 ± 6.87 44 [44, 47] 41.60 ± 6.35 39.16 ± 6.78 0.48

Note that statistical comparison for AARO was not performed for the rTAAD with residual TBAD subgroup due to small number of subjects. Statistically significant differences are highlighted in bold.

*P < 0.05. TBAD, type B aortic dissection; TAAD, type A aortic dissection. Data for the rTAAD with AARO patient group is presented as median [min, max].