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. 2022 Jun 9;9:872481. doi: 10.3389/fmed.2022.872481

Table 1.

Demographic and clinical characteristics of patients with endometrioma.

Demographic or characteristic No. of patients %
Age (years), (M ± SD) 32.63 ± 0.29
BMI (kg/m2), (M ± SD) 21.00 ± 0.14
Complaint, n (%)
Ultrasound-cyst 259 80.2
Dysmenorrhea 16 5.0
Dysmenorrhea-heavy 18 5.6
Infertility 12 3.7
Other symptoms 18 5.6
Parity, n (%)
≥1 98 30.3
Infertility, n (%)
Primary infertility 39 12.1
Second infertility 22 6.8
Dysmenorrhea, n (%)
Mild (VAS 1–4) 44 13.6
Moderate-heavy (VAS 5–10) 208 64.4
Chronic pelvic pain, n (%) 54 16.7
CA125 [n (%)]
≤ 35 IU/ml 85 26.3
>35 IU/ml 238 73.7
Prior endometrioma surgery, n (%) 16 5
Preoperative GnRH-a treatment, n (%) 70 21.7
Endometrial cyst localization, n (%)
Left ovary 94 29.1
Right ovary 80 24.8
Both side 149 46.1
Sum of cyst diameters, n (%)
≤ 10 cm 244 75.7
>10 cm 79 24.5
Deep endometriosis, n (%) 177 54.8
Uterine fibroids, n (%) 57 17.6
Adenomyosis, n (%) 128 39.6
r-ASRM stage, n (%)
I 1 0.3
II 8 2.5
III 102 31.6
IV 212 65.6
Postoperative treatment
COCs, n (%) 12 3.7
COCs duration (months), median (IQR) 6 (4.5–12)
LNG-IUD, n (%) 13 4.0
GnRH-a, n (%) 236 73.1
GnRH-a + LNG-IUD, n (%) 62 19.2
GnRH-a duration (months), median (IQR) 3 (3–3)
LNG-IUD duration (months), median (IQR) 60 (45.75–60.0)
Postoperative pregnancy, n (%)
Natural pregnancy 104 32.2
Assisted reproductive technology 25 7.7
Natural abortion 3 0.9
Follow-up time (months), median (IQR) 84 (72–96)
Recurrence, n (%)
Ultrasound-Endometrioma 21 6.5
Endometriosis related pain 34 10.5
Both 10 3.1

M ± SD, Mean and standard deviation; BMI, Body mass index; VAS, Visual Analog Scale; GnRH-a, Gonadotropin-releasing hormone agonist; r-ASRM, American Society for Reproductive Medicine revised staging system; IQR, Interquartile range; COCs, Combined oral contraceptives; LNG-IUD, Levonorgestrel-releasing intrauterine device.