TABLE 9.

Weighted odds ratios (95% confidence intervals) for insulin resistance (HOMA-IR) of participants without metabolic syndrome across quartiles of serum uric acid (Men = 2,124, Women = 2,146).

		Crudea	Model 1a	Model 2a
Males†
Q1	584/2,124	1.00 (Ref.)	1.00 (Ref.)	1.00 (Ref.)
Q2	538/2,124	1.4 (0.9–2.3) *	1.4 (0.9–2.3)	1.2 (0.7–1.9)
Q3	493/2,124	2.1 (1.4–3.1) **	2.1 (1.4–3.2) **	1.3 (0.8–2.1)
Q4	509/2,124	3.4 (2.3–4.9) **	3.4 (2.4–5.0) **	1.6 (1.1–2.3) *
Females†
Q1	607/2,146	1.00 (Ref.)	1.00 (Ref.)	1.00 (Ref.)
Q2	515/2,146	1.3 (0.9–1.9)	1.4 (1.0–2.1)	1.3 (0.7–2.2)
Q3	503/2,146	2.1 (1.4–3.1) **	2.2 (1.4–3.4) **	1.7 (1.0–2.9)
Q4	521/2,146	3.4 (2.1–5.6) **	3.7 (2.2–6.1) **	1.9 (1.1–3.5) *

^aCalculated using binary logistic regression.

^†Males: Q1 (uric acid ≤ 309.30 μmol/L), Q2 (309.30 < uric acid ≤ 350.90 μmol/L), Q3 (350.90 < uric acid ≤ 398.50 μmol/L), and Q4 (uric acid > 398.50 μmol/L). Females: Q1 (uric acid ≤ 232.00 μmol/L), Q2 (232.00 < uric acid ≤ 267.70 μmol/L), Q3 (267.70 < uric acid ≤ 309.30 μmol/L), and Q4 (uric acid > 309.30 μmol/L).

Model 1 adjusted for race.

Model 2 adjusted for race, body mass index, waist circumference, drinking status, education level, hypertension, serum triglyceride, total cholesterol, and urate-lowering therapy.

*P < 0.05.

**P < 0.01.