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. 2022 Jun 9;13:903755. doi: 10.3389/fimmu.2022.903755

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Copyright © 2022 Paudyal, Mwangi, Rijal, Schwartz, Noble, Shaw, Sealy, Bonnet-Di Placido, Graham, Townsend, Hammond and Tchilian

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Complement dependent cytotoxicity mediated by pig IgG subclasses. (A) CDCC activity of IgG subclasses were measured on MDCK-HA incubated with a serial dilution of pb27 and pb39 IgG subclasses in the presence of rabbit complement and (B) pig complement. Error bar represents the SD of 3 independent experiments. (C) CDCC activity of immune sera was measured in the presence of rabbit complement, error bar represents SEM, n=6.